Method of selectively destroying neoplastic cells

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United States of America Patent

PATENT NO 5688773
SERIAL NO

08330523

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Abstract

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A method for selectively killing nervous system and peripheral neoplastic cells is provided. Viral vectors are used to selectively express a cytochrome P450 gene in neoplastic cells, whose gene product targets the cells for selective killing, by rendering the cells sensitive to a chemotherapeutic agent.

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Patent Owner(s)

Patent OwnerAddress
DANA-FARBER CANCER INSTITUTE450 BROOKLINE AVENUE BOSTON MA 02215
BOSTON UNIVERSITY108 BAY STATE ROAD BOSTON MA 02215

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Breakefield, Xandra O Newton, MA 51 718
Chen, Ling Brookline, MA 357 17312
Chiocca, E Antonio Boston, MA 14 156
Waxman, David J Newton Centre, MA 3 66
Wei, Ming X Somerville, MA 2 36

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