Monoclonal antibodies for inducing tolerance
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United States of America Patent
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Nov 25, 1997
Grant Date -
N/A
app pub date -
Aug 12, 1994
filing date -
May 31, 1989
priority date (Note) -
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Abstract
Tolerance to an antigen is induced in a subject by administering a non-depleting CD4 monoclonal antibody and a non-depleting CD8 monoclonal antibody. Tolerance to the antigen can be induced under cover of these antibodies. A depleting CD4 monoclonal antibody and/or a depicting CD8 monoclonal antibody may be administered prior to the non-depleting antibodies.
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