Quinoline and pyridine anchors for HMG-CoA reductase inhibitors
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United States of America Patent
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Nov 25, 1997
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N/A
app pub date -
Oct 31, 1995
filing date -
Aug 29, 1988
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Abstract
Compounds which are useful as inhibitors of cholesterol biosynthesis and thus as hypocholesterolemic agents are provided which have a quinoline or a pyridine anchor attached by means of a linker to a binding domain sidechain, which compounds inhibit the enzyme 3-hydroxy-3-methyl-glutaryl-coenzyme A reductase.
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