5-(2-imidazolinylamino)benzimidazole compounds useful as alpha-2-adrenoceptor agonists

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United States of America Patent

PATENT NO 5691370
SERIAL NO

08675745

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Abstract

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The subject invention involves compounds having the following structure: ##STR1## wherein: (a) R is unsubstituted C.sub.1 -C.sub.3 alkanyl or alkenyl; (b) R' is selected from hydrogen; unsubstituted C.sub.1 -C.sub.3 alkanyl or alkenyl; unsubstituted C.sub.1 -C.sub.3 alkylthio or alkoxy; hydroxy; thiol; cyano; and halo; and (c) R' is selected from hydrogen, methyl, ethyl and i-propyl. The subject invention also involves pharmaceutical compositions containing such novel compounds, compositions thereof and the use of such compounds for preventing or treating respiratory, ocular and/or gastrointestinal disorders.

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Patent Owner(s)

Patent OwnerAddress
THE BOARD OF REGENTS OF THE UNIVERSITY OF NEBRASKA3835 HOLDREGE STREET VARNER HALL LINCOLN NE 68583

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Bogdan, Sophie Eva Maineville, OH 10 65
Cupps, Thomas Lee Oxford, OH 16 110

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