Diaryl-5-oxygenated-2-(5H) -furanones as COX-2 inhibitors

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United States of America Patent

PATENT NO 5691374
SERIAL NO

08443620

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Abstract

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The invention encompasses the novel compound of Formula I as well as a method of treating cyclooxygenase-2 mediated diseases comprising administration to a patient in need of such treatment of a non-toxic therapeutically effective amount of a compound of Formula I. ##STR1## The invention also encompasses certain pharmaceutical compositions for treatment of cyclooxygenase-2 mediated diseases comprising compounds of Formula I.

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Patent Owner(s)

Patent OwnerAddress
MERCK FROSST COMPANY16711 TRANS-CANADA HIGHWAY KIRKLAND QUEBEC H9H 3L1

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Black, Cameron Point Claire, CA 51 1453
Grimm, Erich Baie D'Urfe, CA 12 167
Leger, Serge Dollard des Ormeaux, CA 57 1487
Wang, Zhaoyin Pierrefonds, CA 73 1827

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