Producing immunogenic constructs using soluble carbohydrates activated via organic cyanylating reagents

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United States of America Patent

PATENT NO 5693326
SERIAL NO

08456694

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ATTORNEY / AGENT: (SPONSORED)

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Abstract

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The invention relates to a process for producing an immunogenic construct comprising activating at least one first carbohydrate-containing moiety with CDAP, and covalently joining the activated first moiety to a second moiety. Preferably, the first moiety is a polysaccharide and the second moiety is a protein. Immunogenic constructs are prepared by this process using either direct or indirect conjugation of the first and second moieties.

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Patent Owner(s)

Patent OwnerAddress
HENRY M JACKSON FOUNDATION FOR THE ADVANCEMENT OF MILITARY MEDICINE THEROCKVILLE MD

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Lees, Andrew Silver Spring, MD 68 828

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