Sustained release formulation containing three different types of polymers
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United States of America Patent
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-
Dec 9, 1997
Grant Date -
N/A
app pub date -
Mar 1, 1995
filing date -
Mar 1, 1995
priority date (Note) -
In Force
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Importance
Abstract
Verapamil depot drug formulations include the pharmaceutical itself and a three component release rate controlling matrix composition. The three components of the matrix composition are (1) an alginate component, such as sodium alginate, (2) an enteric polymer component, such as methacrylic acid copolymer, and (3) a pH independent gelling polymer, such as hydroxypropyl methylcellulose or polyethyleneoxide. The drug release rate can be adjusted by changing the amount of one or more of these components of the composition.
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