Inhibition of reverse transcriptase by phosphorodithioates

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United States of America Patent

PATENT NO 5695979
SERIAL NO

08411474

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Abstract

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The present invention describes a method for the inhibition of reverse transcriptase by contacting said reverse transcriptase with oligonucleotides having have at least one phosphorodithioate internucleotide linkage of the formula ##STR1## within the phosphorus backbone of the oligonucleotide.

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Patent Owner(s)

  • COMPETITIVE TECHNOLOGIES, INC.

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Brill, Wolfgang Freiburg, DE 4 550
Caruthers, Marvin H Boulder, CO 45 6616
Marshall, William S Boulder, CO 18 1055
Nielsen, John Horsholm, DE 44 1135

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