Method of reducing immunogenicity
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United States of America Patent
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Dec 16, 1997
Grant Date -
N/A
app pub date -
Jun 1, 1995
filing date -
Jul 5, 1985
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Abstract
The immunogenicity of avidin, a therapeutic agent moiety of a conjugate, or a targeting composition is reduced by coupling the immunogenic agent with a carbohydrate polymer or polyol groups, such as polysaccharides (e.g. dextran), polyethylene glycol and the like.
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