Hydrogels of absorbable polyoxaesters containing amines or amido groups
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United States of America Patent
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Dec 23, 1997
Grant Date -
N/A
app pub date -
Nov 6, 1996
filing date -
Mar 6, 1995
priority date (Note) -
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Abstract
The present invention describes a crosslinked aliphatic polyoxaesters containing amines and/or amido groups and blends thereof with other polymers that may be used to produce surgical devices such as sutures, sutures with attached needles, molded devices, and the like. The crosslinked aliphatic polyoxaesters of the present invention is formed from an aliphatic polyoxaester having a first divalent repeating unit of formula I: ?O--C(O)--C(R.sub.1)(R.sub.2)--O--(R.sub.3)--O--C(R.sub.1)(R.sub.2)--C(O)--!I and a second repeating unit of the formula: ?--O--R.sub.12 --!.sub.U, XVI and optionally a third repeating unit with a formula selected from the group consisting of: ?--O--R.sub.4 --!.sub.A, II ?--O--R.sub.5 --C(O)--!.sub.B, III (?--O--R.sub.5 --C(O)!.sub.P --O--).sub.L G XI and combinations thereof wherein R.sub.12 contains an internal amine or internal amide group wherein the aliphatic polyoxaester has been crosslinked.
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