Methods of treating cancerous cells with anti-receptor antibodies
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United States of America Patent
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Jan 6, 1998
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N/A
app pub date -
Nov 30, 1994
filing date -
Jul 27, 1989
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Abstract
The present invention provides methods and therapeutic compositions for treatment of mammalian tumors wherein the cells of such tumor express both epidermal growth factor receptor and p185neu, p185c-neu or a homologue of p185neu or p185c-neu and the epidermal growth factor. At least one antibody specific for epidermal growth factor receptor, monoclonal antibody 425, and at least one antibody specific for p185neu, p185c-neu or a homologue of p185neu or p185c-neu, monoclonal antibody 7.16.4, are administered to the mammal in an amount effective to reduce tumor growth.
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