US Patent No: 5,707,385

Number of patents in Portfolio can not be more than 2000

Drug loaded elastic membrane and method for delivery

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Abstract

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An expandable sheath is provided for delivering a therapeutic drug in a body lumen which comprises an expandable membrane with a therapeutic drug incorporated therein. The expandable membrane is in a cylindrical configuration and mounted on the balloon portion of a catheter for intraluminal drug delivery into a patient's vascular system. The expandable membrane may also be mounted on an intravascular stent, both of which are implanted within the patient's vascular system. The therapeutic drug then diffuses into the vascular system at a controlled rate to match a specific clinical need.

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First Claim

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Patent Owner(s)

Patent OwnerAddressTotal Patents
ADVANCED CARDIOVASCULAR SYSTEMS, INC.SANTA CLARA, CA1403

International Classification(s)

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Williams, Michael S Chapel Hill, NC 143 6713

Cited Art Landscape

Patent Info (Count) # Cites Year
 
Other [Check patent profile for assignment information] (12)
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* 5,151,105 Collapsible vessel sleeve implant 457 1991
* 5,330,500 Self-expanding endovascular stent with silicone coating 563 1992
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SOLUTIA INC. (1)
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SHERWOOD SERVICES AG (1)
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ADVANCED CARDIOVASCULAR SYSTEMS, INC. (1)
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ATRIUM MEDICAL CORPORATION (1)
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MedInnovations, Inc. (1)
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CABOT TECHNOLOGY CORPORATION (1)
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MASSACHUSETTS INSTITUTE OF TECHNOLOGY (1)
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UNIVERSITY OF UTAH (1)
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MEDTRONIC AVE, INC. (1)
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COOK MEDICAL TECHNOLOGIES LLC (1)
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Interag (1)
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WAYNE STATE UNIVERSITY (1)
* 5,199,951 Method of drug application in a transporting medium to an arterial wall injured during angioplasty 130 1991
 
CORDIS CORPORATION (3)
* 4,739,762 Expandable intraluminal graft, and method and apparatus for implanting an expandable intraluminal graft 1195 1986
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INTERVASCULAR, INC. (1)
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UNIVERSITY OF MEDICINE AND DENTISTRY OF NEW JERSEY (1)
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OLYMPUS OPTICAL CO., LTD. (2)
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EXPANDABLE GRAFTS PARTNERSHIP, A TX. GENERAL PARTNERSHIP (1)
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EXPANDABLE GRAFTS PARTNERSHIP, 8000 I.H. 10 WEST, STE. 1265, SAN ANTONIO, TX A GENERAL PARTNERSHIP OF TX. (1)
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DUKE UNIVERSITY (2)
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ANGEION CORPORATION (1)
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AMS MEDINVENT S.A. (1)
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EDWARDS LIFESCIENCES CORPORATION (1)
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MAQUET CARDIOVASCULAR LLC (2)
* 5,084,065 Reinforced graft assembly 352 1989
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NISSHO CORPORATION (1)
* 5,236,447 Artificial tubular organ 320 1991
 
BOSTON SCIENTIFIC SCIMED, INC. (5)
* 4,994,033 Intravascular drug delivery dilatation catheter 438 1989
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* 5,197,977 Drug delivery collagen-impregnated synthetic vascular graft 389 1992
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Servetus Partnership (1)
* 4,878,906 Endoprosthesis for repairing a damaged vessel 835 1988
 
ANGIOGUARD, INC. (1)
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* Cited By Examiner

Patent Citation Ranking

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Patent Info (Count) # Cites Year
 
Other [Check patent profile for assignment information] (29)
6,613,082 Stent having cover with drug delivery capability 40 2000
6,379,382 Stent having cover with drug delivery capability 124 2000
6,613,084 Stent having cover with drug delivery capability 79 2001
* 2003/0078,647 Angioplasty stent adapted to counter restenosis, respective kit and components 41 2002
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* 2003/0157,241 Method for coating an implantable device and system for performing the method 15 2003
* 2003/0211,230 Stent mounting assembly and a method of using the same to coat a stent 14 2003
* 2004/0098,117 Composite stent with regioselective material and a method of forming the same 18 2003
* 2004/0186,553 Medicated porous metal prosthesis and a method of making the same 36 2004
* 2004/0166,140 Implantable device for controlled release of drug 59 2004
* 2004/0191,404 Method of making a variable surface area stent 60 2004
* 2004/0243,226 Means and method for the treatment of coronary artery obstructions 0 2004
* 2004/0265,475 Selective coating of medical devices 1 2004
* 2005/0033,411 Surface features of an implantable medical device 47 2004
* 2005/0149,000 Medical device with controlled reservoir opening 12 2005
* 2005/0208,103 Targeted transscleral controlled release drug delivery to the retina and choroid 23 2005
* 2005/0232,971 Biodegradable polymers for use with implantable medical devices 34 2005
* 2006/0271,168 Degradable medical device 33 2006
* 2007/0073,383 Drug-eluting stent cover and method of use 5 2006
* 2006/0271,165 Drug-eluting stent cover and method of use 1 2006
* 2006/0280,770 Coating for implantable devices and a method of forming the same 53 2006
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* 2008/0249,609 EXPANDABLE MEDICAL DEVICE WITH DUCTILE HINGES 7 2008
* 2008/0294,242 EXPANDABLE MEDICAL DEVICE WITH DUCTILE HINGES 0 2008
* 8,974,520 Method for producing a bioactive surface on the balloon of a balloon catheter 0 2009
* 2011/0190,696 Method for Producing a Bioactive Surface on the Balloon of a Balloon Catheter 0 2009
9,254,212 Segmented scaffolds and delivery thereof for peripheral applications 0 2012
9,180,273 Method for loading substances into drug delivery catheter 0 2012
9,254,202 Method and apparatus for loading a beneficial agent into an expandable medical device 0 2013
 
OrbusNeich Medical, Inc. (5)
* 2005/0025,752 Medical device with coating for capturing genetically-altered cells and methods for using same 20 2004
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8,088,060 Progenitor endothelial cell capturing with a drug eluting implantable medical device 2 2006
* 2007/0123,977 Progenitor Endothelial Cell Capturing with a Drug Eluting Implantable Medical Device 25 2006
* 2007/0129,789 Progenitor Endothelial Cell Capturing with a Drug Eluting Implantable Medical Device 51 2006
 
HEMOTEQ AG (4)
8,597,720 Medical product for treating stenosis of body passages and for preventing threatening restenosis 1 2008
* 2010/0179,475 MEDICAL PRODUCT FOR TREATING STENOSIS OF BODY PASSAGES AND FOR PREVENTING THREATENING RESTENOSIS 18 2008
9,192,697 Balloon catheter for treating stenosis of body passages and for preventing threatening restenosis 0 2011
* 2011/0160,698 Balloon Catheter for Treating Stenosis of Body Passages and for Preventing Threatening Restenosis 5 2011
 
VANCE PRODUCTS INCORPORATED (1)
* 2008/0243,103 Medical Device for Delivering a Bioactive and Method of Use Thereof 3 2008
 
Angiotech BioCoatings, Inc. (1)
8,101,200 Targeted therapeutic agent release devices and methods of making and using the same 0 2001
 
IPXMEDICAL, LLC (4)
* 2002/0018,795 Targeted therapeutic agent release devices and methods of making and using the same 25 2001
7,771,468 Medicated stent having multi-layer polymer coating 4 2003
* 2004/0117,007 Medicated stent having multi-layer polymer coating 80 2003
8,287,590 Medicated stent having multi-layer polymer coating 0 2010
 
MEDINOL LTD. (3)
7,959,664 Flat process of drug coating for stents 2 2006
* 2007/0077,347 Flat process of drug coating for stents 33 2006
8,828,077 Flat process of preparing drug eluting stents 0 2011
 
FEMSUITE LLC (1)
* 2005/0021,069 Inflatable apparatus for accessing body cavity and methods of making 2 2004
 
Quanam Medical Corporation (5)
6,653,426 Polymer compositions for intraluminal stent 35 2002
7,115,691 Polymer compositions for intraluminal stent 7 2003
* 2004/0059,408 Polymer compositions for intraluminal stent 9 2003
7,374,570 Polymer compositions for intraluminal stent 3 2006
* 2007/0073,016 Polymer compositions for intraluminal stent 4 2006
 
TRANSAMERICA BUSINESS CREDIT CORPORATION (1)
6,363,938 Methods and apparatus for perfusing tissue and/or stimulating revascularization and tissue growth 112 1998
 
CONOR MEDSYSTEMS, INC. (3)
7,208,010 Expandable medical device for delivery of beneficial agent 36 2001
7,208,011 Implantable medical device with drug filled holes 79 2002
* 2003/0068,355 Therapeutic agent delivery device with protective separating layer 19 2002
 
WILLIAM COOK EUROPE APS (1)
* 2011/0015,725 COATED MEDICAL DEVICE 3 2010
 
SONNAX INDUSTRIES, INC. (1)
* 2004/0236,410 Polymeric body formation 3 2003
 
ETHICON, INC. (1)
* 2005/0171,603 Expanding ligament graft fixation system and method 39 2005
 
SPECIALTY COATING SYSTEMS, INC. (2)
* 2006/0083,770 Medical devices and methods of preparation and use 4 2004
* 2007/0148,390 Fluorinated coatings 5 2005
 
INNOVATIONS HOLDINGS, L.L.C. (44)
* 6,562,065 Expandable medical device with beneficial agent delivery mechanism 112 2000
6,855,125 Expandable medical device delivery system and method 60 2001
* 2001/0027,291 Expandable medical device delivery system and method 17 2001
6,527,799 Expandable medical device with ductile hinges 117 2001
6,764,507 Expandable medical device with improved spatial distribution 86 2001
6,964,680 Expandable medical device with tapered hinge 31 2002
* 2002/0107,563 Expandable medical device with locking mechanism 5 2002
* 2003/0009,214 Medical device with beneficial agent delivery mechanism 86 2002
7,819,912 Expandable medical device with beneficial agent delivery mechanism 0 2003
7,056,338 Therapeutic agent delivery device with controlled therapeutic agent release rates 85 2003
* 2004/0193,255 Therapeutic agent delivery device with controlled therapeutic agent release rates 6 2003
* 2004/0073,294 Method and apparatus for loading a beneficial agent into an expandable medical device 23 2003
7,179,288 Expandable medical device for delivery of beneficial agent 19 2003
7,169,179 Drug delivery device and method for bi-directional drug delivery 15 2003
* 2004/0127,977 Expandable medical device with openings for delivery of multiple beneficial agents 53 2003
* 2004/0127,976 Method and apparatus for loading a beneficial agent into an expandable medical device 55 2003
* 2004/0143,322 Method and apparatus for treating vulnerable artherosclerotic plaque 60 2003
* 2004/0143,321 Expandable medical device and method for treating chronic total occlusions with local delivery of an angiogenic factor 73 2003
* 2004/0142,014 Method and apparatus for reducing tissue damage after ischemic injury 72 2003
* 2005/0010,170 IMPLANTABLE MEDICAL DEVICE WITH BENEFICIAL AGENT CONCENTRATION GRADIENT 5 2004
* 2004/0204,756 ABSORBENT ARTICLE WITH IMPROVED LIQUID ACQUISITION CAPACITY 14 2004
* 2004/0202,692 Implantable medical device and method for in situ selective modulation of agent delivery 78 2004
7,896,912 Expandable medical device with S-shaped bridging elements 2 2004
* 2004/0193,249 Expandable medical device with S-shaped bridging elements 1 2004
D516723 Stent wall structure 17 2004
7,517,362 Therapeutic agent delivery device with controlled therapeutic agent release rates 3 2004
* 2005/0058,684 Therapeutic agent delivery device with controlled therapeutic agent release rates 20 2004
D523558 Stent wall structure 17 2005
8,187,321 Expandable medical device for delivery of beneficial agent 0 2005
* 2006/0009,838 Expandable medical device for delivery of beneficial agent 12 2005
* 2006/0008,503 Therapeutic agent delivery device with controlled therapeutic agent release rates 12 2005
7,850,727 Expandable medical device for delivery of beneficial agent 5 2005
7,842,083 Expandable medical device with improved spatial distribution 1 2006
7,850,728 Expandable medical device for delivery of beneficial agent 2 2006
* 2006/0149,357 Expandable medical device for delivery of beneficial agent 0 2006
8,449,901 Implantable medical device with beneficial agent concentration gradient 0 2006
* 2006/0147,489 Implantable medical device with beneficial agent concentration gradient 12 2006
* 2006/0178,735 Expandable medical device and method for treating chronic total occlusions with local delivery of an angiogenic factor 12 2006
8,052,734 Expandable medical device with beneficial agent delivery mechanism 1 2008
8,052,735 Expandable medical device with ductile hinges 0 2008
8,349,390 Method and apparatus for loading a beneficial agent into an expandable medical device 0 2010
8,197,881 Method and apparatus for loading a beneficial agent into an expandable medical device 0 2010
* 2011/0048,574 METHOD AND APPARATUS FOR LOADING A BENEFICIAL AGENT INTO AN EXPANDABLE MEDICAL DEVICE 0 2010
8,439,968 Expandable medical device for delivery of beneficial agent 2 2011
 
SAN FANG CHEMICAL INDUSTRY CO., LTD. (3)
7,789,738 Sheet for mounting polishing workpiece and method for making the same 0 2006
* 7,629,554 Sheet for mounting polishing workpiece and method for making the same 0 2007
* 2009/0252,876 SHEET FOR MOUNTING POLISHING WORKPIECE AND METHOD FOR MAKING THE SAME 0 2009
 
VEGENICS PTY LTD (4)
6,958,147 Use of VEGF-C to prevent restenosis 15 1999
8,455,453 Use of VEGF-D gene to prevent restenosis 0 2005
* 2005/0256,075 Use of VEGF-C or VEGF-D gene or protein to prevent restenosis 9 2005
8,278,098 Materials and methods involving hybrid vascular endothelial growth factor DNAs and proteins 1 2011
 
DIETCH, LAURA N. (1)
* 2008/0140,002 SYSTEM FOR DELIVERY OF BIOLOGICALLY ACTIVE SUBSTANCES WITH ACTUATING THREE DIMENSIONAL SURFACE 72 2007
 
CORDIS CORPORATION (8)
6,585,764 Stent with therapeutically active dosage of rapamycin coated thereon 197 2001
* 2002/0051,730 Coated medical devices and sterilization thereof 305 2001
6,808,536 Stent containing rapamycin or its analogs using a modified stent 61 2003
7,223,286 Local delivery of rapamycin for treatment of proliferative sequelae associated with PTCA procedures, including delivery using a modified stent 35 2004
7,229,473 Local delivery of rapamycin for treatment of proliferative sequelae associated with PTCA procedures, including delivery using a modified stent 35 2006
7,217,286 Local delivery of rapamycin for treatment of proliferative sequelae associated with PTCA procedures, including delivery using a modified stent 25 2006
7,666,222 Methods and devices for delivering therapeutic agents to target vessels 8 2006
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Diseno y Desarrollo Medica, S.A. de C.V. (2)
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6,254,627 Non-thrombogenic stent jacket 46 1998
 
Design & Performance- Cyprus Limited (3)
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8,882,822 Non-thrombogenic stent jacket 0 2005
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DEPUY SYNTHES PRODUCTS, LLC (1)
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BIOTRONIK VI PATENT AG (1)
* 2009/0270,977 STENT FIXATION SYSTEM 0 2009
 
SORIN BIOMEDICA S.P.A. (1)
6,491,720 Angioplasty stent adapted to counter restenosis respective kit and components 56 2000
 
SORIN BIOMEDICA CARDIO S.R.L. (1)
6,585,632 Device for conveying radioactive agents on angioplasty stents, respective method and kit 14 2002
 
TELEFLEX MEDICAL INCORPORATED (1)
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CID S.P.A. (1)
6,447,439 Device for conveying radioactive agents on angioplasty stents, respective method and kit 11 2000
 
ISRAEL AIRCRAFT INDUSTRIES LTD. (2)
6,585,759 Method and apparatus for manufacturing medical support devices 4 1999
7,278,195 Method for producing a coated medical support device 1 2003
 
MED INSTITUTE, INC. (4)
7,731,685 Coated medical device 15 2005
7,867,275 Coated implantable medical device method 0 2006
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7,846,202 Coated implantable medical device 0 2007
 
Abbott Laboratories Vascular Enterprises Limited (1)
* 2005/0143,752 Cold-molding process for loading a stent onto a stent delivery system 19 2005
 
SYNTACH AG (5)
* 2006/0116,666 Two-stage scar generation for treating atrial fibrillation 0 2005
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8,840,658 Electrical conduction block implant device 0 2009
8,257,376 Device, a kit and a method for treatment of disorders in the heart rhythm regulation system 3 2009
8,409,268 Electrical conduction block implant device 1 2010
 
MEDTRONIC VASCULAR, INC. (8)
* 7,670,329 Systems and methods for delivering drugs to selected locations within the body 32 2006
* 2007/0021,730 Systems and Methods for Delivering Drugs to Selected Locations Within the Body 15 2006
8,070,720 Methods for incorporating a drug into an elastomeric medical device 1 2008
* 2009/0182,273 Methods for Incorporating a Drug into an Elastomeric Medical Device 18 2008
* 8,083,708 Systems and methods for delivering drugs to selected locations within the body 2 2010
* 2010/0324,471 Systems and Methods for Delivering Drugs to Selected Locations Within the Body 9 2010
8,540,694 Systems and methods for delivering drugs to selected locations within the body 0 2011
8,998,977 Hollow drug-filled stent and method of forming hollow drug-filled stent 0 2012
 
The Penn State Research Foundation (1)
* 6,682,545 System and device for preventing restenosis in body vessels 58 2000
 
ADVANCED BIO PROSTHETIC SURFACES, LTD. (2)
9,107,605 Device for in vivo delivery of bioactive agents and method of manufacture thereof 0 2004
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ENDOTEX INTERNATIONAL SYSTEMS, INC. (1)
* 5,824,054 Coiled sheet graft stent and methods of making and use 179 1997
 
Abbott Cardiovascular Systems Inc. (58)
* 2006/0216,431 Electrostatic abluminal coating of a stent crimped on a balloon catheter 26 2005
7,964,210 Degradable polymeric implantable medical devices with a continuous phase and discrete phase 2 2006
* 2007/0231,365 Degradable polymeric implantable medical devices with a continuous phase and discrete phase 32 2006
7,985,441 Purification of polymers for coating applications 5 2006
8,603,530 Nanoshell therapy 0 2006
* 2007/0292,518 Nanoshell therapy 41 2006
8,048,448 Nanoshells for drug delivery 2 2006
8,333,000 Methods for improving stent retention on a balloon catheter 2 2006
8,017,237 Nanoshells on polymers 3 2006
9,173,733 Tracheobronchial implantable medical device and methods of use 0 2006
8,099,849 Optimizing fracture toughness of polymeric stent 3 2006
8,961,584 Composite stent with regioselective material 0 2006
8,025,916 Methods for forming a composite stent with regioselective material 1 2006
8,343,530 Polymer-and polymer blend-bioceramic composite implantable medical devices 2 2006
* 2007/0282,426 Polymer-and polymer blend-bioceramic composite implantable medical devices 15 2006
* 2007/0278,720 Implantable medical devices made from polymer-bioceramic composite 7 2007
* 2008/0243,228 Implantable medical devices fabricated from block copolymers 12 2007
8,486,135 Implantable medical devices fabricated from branched polymers 0 2007
8,262,723 Implantable medical devices fabricated from polymer blends with star-block copolymers 0 2007
8,034,287 Radiation sterilization of medical devices 12 2007
* 2007/0280,851 Radiation sterilization of medical devices 20 2007
7,951,194 Bioabsorbable stent with radiopaque coating 5 2007
7,829,008 Fabricating a stent from a blow molded tube 6 2007
* 2008/0300,670 Fabricating a stent from a blow molded tube 8 2007
7,959,857 Radiation sterilization of medical devices 8 2007
* 2008/0299,002 Radiation sterilization of medical devices 7 2007
8,293,260 Elastomeric copolymer coatings containing poly (tetramethyl carbonate) for implantable medical devices 2 2007
8,202,528 Implantable medical devices with elastomeric block copolymer coatings 4 2007
* 2008/0306,582 Implantable medical devices with elastomeric copolymer coatings 2 2007
* 2008/0306,591 Implantable medical devices with elastomeric block copolymer coatings 7 2007
8,425,591 Methods of forming polymer-bioceramic composite medical devices with bioceramic particles 1 2007
8,535,372 Bioabsorbable stent with prohealing layer 1 2007
8,128,688 Carbon coating on an implantable device 0 2007
* 2007/0298,354 Carbon coating on an implantable device 6 2007
8,048,441 Nanobead releasing medical devices 3 2007
8,016,879 Drug delivery after biodegradation of the stent scaffolding 6 2007
7,901,452 Method to fabricate a stent having selected morphology to reduce restenosis 20 2007
7,823,263 Method of removing stent islands from a stent 1 2007
* 2008/0113,081 Methods for Modifying Balloon of a Catheter Assembly 20 2008
8,435,550 Anti-proliferative and anti-inflammatory agent combination for treatment of vascular disorders with an implantable medical device 1 2008
* 2009/0286,761 Anti-Proliferative and Anti-Inflammatory Agent Combination for Treatment of Vascular Disorders with an Implantable Medical Device 11 2008
8,226,603 Expandable member having a covering formed of a fibrous matrix for intraluminal drug delivery 2 2008
8,049,061 Expandable member formed of a fibrous matrix having hydrogel polymer for intraluminal drug delivery 4 2008
* 2010/0076,401 Expandable Member Having A Covering Formed Of A Fibrous Matrix For Intraluminal Drug Delivery 13 2008
8,076,529 Expandable member formed of a fibrous matrix for intraluminal drug delivery 0 2008
* 2010/0285,085 BALLOON COATING WITH DRUG TRANSFER CONTROL VIA COATING THICKNESS 28 2009
8,425,587 Method of treatment with a bioabsorbable stent with time dependent structure and properties and regio-selective degradation 1 2009
* 2011/0066,225 Bioabsorbable Stent With Time Dependent Structure And Properties And Regio-Selective Degradation 5 2009
8,500,687 Stent delivery system having a fibrous matrix covering with improved stent retention 0 2011
8,585,754 Stent formed of a Biodegradable material 0 2012
8,925,177 Methods for improving stent retention on a balloon catheter 0 2012
8,592,036 Nanoshells on polymers 0 2012
8,808,342 Nanoshell therapy 0 2013
8,752,267 Method of making stents with radiopaque markers 0 2013
8,752,268 Method of making stents with radiopaque markers 1 2013
RE45744 Temperature controlled crimping 0 2013
9,198,785 Crush recoverable polymer scaffolds 0 2013
9,038,260 Stent with radiopaque markers 0 2014
 
KENSEY NASH CORPORATION (1)
* 2003/0074,049 Covered stents and systems for deploying covered stents 74 2002
 
ADVANCED CARDIOVASCULAR SYSTEMS, INC. (165)
* 5,843,172 Porous medicated stent 412 1997
6,527,801 Biodegradable drug delivery material for stent 333 2000
6,555,157 Method for coating an implantable device and system for performing the method 284 2000
* 6,585,926 Method of manufacturing a porous balloon 202 2000
6,805,898 Surface features of an implantable medical device 200 2000
6,783,793 Selective coating of medical devices 79 2000
6,558,733 Method for etching a micropatterned microdepot prosthesis 314 2000
6,641,607 Double tube stent 98 2000
6,635,082 Radiopaque stent 94 2000
6,764,505 Variable surface area stent 322 2001
7,862,495 Radiation or drug delivery source with activity gradient to minimize edge effects 1 2001
* 2002/0183,581 Radiation or drug delivery source with activity gradient to minimize edge effects 218 2001
6,723,120 Medicated porous metal prosthesis 226 2002
7,169,178 Stent with drug coating 80 2002
7,144,422 Drug-eluting stent and methods of making the same 23 2002
7,105,018 Drug-eluting stent cover and method of use 77 2002
7,470,283 Biodegradable drug delivery material for stent 11 2003
7,390,333 Biodegradable drug delivery material for stent 18 2003
6,860,946 System for the process of coating implantable medical devices 60 2003
7,258,891 Stent mounting assembly and a method of using the same to coat a stent 22 2003
7,186,789 Bioabsorbable, biobeneficial polyester polymers for use in drug eluting stent coatings 19 2003
* 2004/0253,203 Bioabsorbable, biobeneficial polyester polymers for use in drug eluting stent coatings 42 2003
7,285,304 Fluid treatment of a polymeric coating on an implantable medical device 32 2003
* 7,435,255 Drug-eluting stent and methods of making 6 2003
7,169,173 Composite stent with regioselective material and a method of forming the same 26 2003
7,198,675 Stent mandrel fixture and method for selectively coating surfaces of a stent 65 2003
* 2005/0069,630 Stent mandrel fixture and method for selectively coating surfaces of a stent 82 2003
* 2005/0118,344 Temperature controlled crimping 60 2003
7,563,324 System and method for coating an implantable medical device 48 2003
7,699,890 Medicated porous metal prosthesis and a method of making the same 3 2004
* 2005/0214,339 Biologically degradable compositions for medical applications 18 2004
7,674,493 Method of making a variable surface area stent 1 2004
* 2005/0226,991 Methods for modifying balloon of a catheter assembly 14 2004
7,553,377 Apparatus and method for electrostatic coating of an abluminal stent surface 18 2004
* 2005/0265,960 Polymers containing poly(ester amides) and agents for use with medical articles and methods of fabricating the same 52 2004
7,329,366 Method of polishing implantable medical devices to lower thrombogenecity and increase mechanical stability 13 2004
7,077,860 Method of reducing or eliminating thrombus formation 31 2004
8,568,469 Stent locking element and a method of securing a stent on a delivery system 0 2004
8,172,897 Polymer and metal composite implantable medical devices 1 2004
* 2005/0209,680 Polymer and metal composite implantable medical devices 54 2004
7,297,159 Selective coating of medical devices 10 2004
* 2006/0020,330 Method of fabricating an implantable medical device with biaxially oriented polymers 39 2004
7,335,314 Method of making an implantable medical device 19 2004
* 2006/0047,336 Stent-catheter assembly with a releasable connection for stent retention 31 2004
7,648,727 Methods for manufacturing a coated stent-balloon assembly 6 2004
* 2006/0043,650 Methods for manufacturing a coated stent-balloon assembly 13 2004
7,229,471 Compositions containing fast-leaching plasticizers for improved performance of medical devices 83 2004
* 2006/0058,868 Compositions containing fast-leaching plasticizers for improved performance of medical devices 51 2004
8,778,256 Deformation of a polymer tube in the fabrication of a medical article 1 2004
8,173,062 Controlled deformation of a polymer tube in fabricating a medical article 6 2004
8,043,553 Controlled deformation of a polymer tube with a restraining surface in fabricating a medical article 13 2004
8,052,912 Temperature controlled crimping 1 2004
7,632,307 Abluminal, multilayer coating constructs for drug-delivery stents 12 2004
7,758,881 Anti-proliferative and anti-inflammatory agent combination for treatment of vascular disorders with an implantable medical device 5 2005
* 2006/0002,977 Anti-proliferative and anti-inflammatory agent combination for treatment of vascular disorders with an implantable medical device 14 2005
* 2006/0224,226 In-vivo radial orientation of a polymeric implantable medical device 26 2005
7,381,048 Stents with profiles for gripping a balloon catheter and molds for fabricating stents 3 2005
* 2006/0229,695 Stents with profiles for gripping a balloon catheter and molds for fabricating stents 2 2005
7,291,166 Polymeric stent patterns 26 2005
7,875,283 Biodegradable polymers for use with implantable medical devices 11 2005
7,622,070 Method of manufacturing an implantable polymeric medical device 51 2005
* 2006/0287,715 Method of manufacturing an implantable polymeric medical device 14 2005
7,823,533 Stent fixture and method for reducing coating defects 3 2005
* 2007/0003,688 Stent fixture and method for reducing coating defects 23 2005
* 2005/0283,229 Coatings for controlling erosion of a substrate of an implantable medical device 51 2005
7,875,233 Method of fabricating a biaxially oriented implantable medical device 11 2005
* 2005/0288,481 Design of poly(ester amides) for the control of agent-release from polymeric compositions 57 2005
7,735,449 Stent fixture having rounded support structures and method for use thereof 12 2005
7,658,880 Polymeric stent polishing method and apparatus 6 2005
* 2007/0023,974 Polymeric stent polishing method and apparatus 6 2005
7,297,758 Method for extending shelf-life of constructs of semi-crystallizable polymers 3 2005
* 2007/0032,634 Method for extending shelf-life of constructs of semi-crystallizable polymers 3 2005
* 2007/0038,290 Fiber reinforced composite stents 49 2005
7,476,245 Polymeric stent patterns 8 2005
* 2007/0043,426 Polymeric stent patterns 9 2005
9,248,034 Controlled disintegrating implantable medical devices 0 2005
* 2007/0055,364 Controlled disintegrating implantable medical devices 40 2005
* 2007/0045,252 Laser induced plasma machining with a process gas 21 2005
* 2007/0045,255 Laser induced plasma machining with an optimized process gas 11 2005
7,985,440 Method of using a mandrel to coat a stent 5 2005
* 2006/0065,193 Device for supporting a stent during coating of the stent 4 2005
* 2006/0035,012 Method of using a mandrel to coat a stent 17 2005
7,867,547 Selectively coating luminal surfaces of stents 0 2005
* 2007/0151,961 Fabrication of an implantable medical device with a modified laser beam 50 2006
* 2007/0156,230 Stents with radiopaque markers 13 2006
7,951,185 Delivery of a stent at an elevated temperature 14 2006
7,989,018 Fluid treatment of a polymeric coating on an implantable medical device 3 2006
* 2006/0246,209 Fluid treatment of a polymeric coating on an implantable medical device 1 2006
8,747,878 Method of fabricating an implantable medical device by controlling crystalline structure 0 2006
8,069,814 Stent support devices 5 2006
8,003,156 Rotatable support elements for stents 10 2006
* 2007/0259,099 Rotatable support elements for stents 10 2006
7,648,725 Clamp mandrel fixture and a method of using the same to minimize coating defects 5 2006
7,572,336 Clamp mandrel fixture and a method of using the same to minimize coating defects 3 2006
* 2006/0207,501 Clamp mandrel fixture and a method of using the same to minimize coating defects 1 2006
7,761,968 Method of crimping a polymeric stent 21 2006
* 2007/0271,763 Method of crimping a polymeric stent 26 2006
7,959,940 Polymer-bioceramic composite implantable medical devices 4 2006
* 2007/0282,431 Polymer-bioceramic composite implantable medical devices 14 2006
8,747,879 Method of fabricating an implantable medical device to reduce chance of late inflammatory response 0 2006
* 2007/0282,433 Stent with retention protrusions formed during crimping 42 2006
* 2007/0281,073 Enhanced adhesion of drug delivery coatings on stents 25 2006
* 2007/0286,941 Surface treatment of a polymeric stent 5 2006
7,731,890 Methods of fabricating stents with enhanced fracture toughness 5 2006
* 2007/0293,938 Methods of fabricating stents with enhanced fracture toughness 35 2006
9,072,820 Polymer composite stent with polymer particles 0 2006
* 2007/0299,504 Polymer composite stent with polymer particles 8 2006
* 2007/0299,511 Thin stent coating 2 2006
7,794,776 Modification of polymer stents with radiation 8 2006
7,740,791 Method of fabricating a stent with features by blow molding 3 2006
* 2008/0001,333 Method of fabricating a stent with features by blow molding 38 2006
* 2008/0009,938 Stent with a radiopaque marker and method for making the same 8 2006
7,998,404 Reduced temperature sterilization of stents 11 2006
7,757,543 Radio frequency identification monitoring of stents 1 2006
* 2008/0014,244 Implantable medical devices and coatings therefor comprising physically crosslinked block copolymers 6 2006
7,794,495 Controlled degradation of stents 10 2006
* 2008/0015,686 Controlled degradation of stents 11 2006
7,886,419 Stent crimping apparatus and method 2 2006
* 2008/0016,668 Stent crimping apparatus and method 16 2006
7,416,558 Drug-eluting stent cover and method of use 48 2006
7,413,574 Drug-eluting stent cover method of use 11 2006
8,128,687 Drug-eluting stent with filament strands 0 2006
* 2006/0287,709 Drug-eluting stent and methods of making the same 25 2006
7,923,022 Degradable polymeric implantable medical devices with continuous phase and discrete phase 6 2006
* 2008/0063,685 Degradable polymeric implantable medical devices with continuous phase and discrete phase 12 2006
* 2007/0282,434 Copolymer-bioceramic composite implantable medical devices 4 2006
7,842,737 Polymer blend-bioceramic composite implantable medical devices 6 2006
7,824,440 Stent with drug coating 3 2006
* 2008/0091,262 Drug delivery after biodegradation of the stent scaffolding 10 2006
7,824,441 Stent with drug coating 3 2006
7,820,229 Method of coating a stent 4 2006
7,666,223 Stent with drug coating 6 2006
* 2007/0055,349 Stent with drug coating 47 2006
* 2007/0055,354 Stent with drug coating 45 2006
* 2007/0116,856 Composite stent with regioselective material 3 2006
* 2007/0118,212 Composite stent with regioselective material 9 2006
7,312,299 Bioabsorbabl, biobeneficial polyester polymers for stent coatings 2 2006
7,301,001 Bioabsorbable, biobeneficial polyester polymers for stent coatings 5 2006
* 2007/0123,689 Bioabsorbable, biobeneficial polyester polymers for stent coatings 2 2006
8,197,879 Method for selectively coating surfaces of a stent 0 2007
7,604,700 Stent mandrel fixture and method for selectively coating surfaces of a stent 1 2007
* 2007/0131,165 Stent mandrel fixture and method for selectively coating surfaces of a stent 1 2007
7,662,326 Compositions containing fast-leaching plasticizers for improved performance of medical devices 1 2007
* 2007/0203,568 Compositions containing fast-leaching plasticizers for improved performance of medical devices 20 2007
7,955,381 Polymer-bioceramic composite implantable medical device with different types of bioceramic particles 2 2007
8,470,014 Stent-catheter assembly with a releasable connection for stent retention 0 2007
* 2008/0033,526 Stent-catheter assembly with a releasable connection for stent retention 7 2007
7,931,931 Medicated porous metal prosthesis and a method of making the same 1 2007
8,109,994 Biodegradable drug delivery material for stent 4 2008
7,967,998 Method of polishing implantable medical devices to lower thrombogenecity and increase mechanical stability 0 2008
* 2008/0099,442 METHOD OF POLISHING IMPLANTABLE MEDICAL DEVICES TO LOWER THROMBOGENECITY AND INCREASE MECHANICAL STABILITY 1 2008
7,708,548 Molds for fabricating stents with profiles for gripping a balloon catheter 1 2008
8,846,070 Biologically degradable compositions for medical applications 0 2008
8,007,529 Medicated porous metal prosthesis 10 2008
* 2008/0288,058 MEDICATED POROUS METAL PROSTHESIS AND A METHOD OF MAKING THE SAME 1 2008
8,414,642 Biodegradable stent of a polyorthoester polymer or a polyanhydride polymer 0 2008
* 2009/0082,853 BIODEGRADABLE DRUG DELIVERY MATERIAL FOR STENT 2 2008
8,119,184 Method of making a variable surface area stent 2 2010
8,586,125 Thermal treatment of an implantable medical device 2 2010
* 2011/0008,529 Thermal Treatment Of An Implantable Medical Device 5 2010
8,293,367 Nanoshells on polymers 1 2011
8,741,379 Rotatable support elements for stents 1 2011
8,637,110 Rotatable support elements for stents 1 2011
8,596,215 Rotatable support elements for stents 1 2011
8,465,789 Rotatable support elements for stents 1 2011
 
ATRIUM MEDICAL CORPORATION (5)
6,955,661 Expandable fluoropolymer device for delivery of therapeutic agents and method of making 83 1999
7,637,886 Expandable fluoropolymer device and method of making 5 2002
* 2002/0183,716 Expandable fluoropolymer device and method of making 30 2002
* 2004/0236,278 Therapeutic agent delivery 6 2003
9,050,442 Expandable fluoropolymer device for delivery of therapeutic agents and method of making 0 2010
 
MASSACHUSETTS EYE & EAR INFIRMARY (2)
7,563,255 Implantable drug delivery device and use thereof 19 2002
* 2005/0175,708 Drug delivery systems and use thereof 23 2004
 
TRANSVASCULAR, INC. (2)
* 7,094,230 Systems and methods for delivering drugs to selected locations within the body 45 2003
* 2004/0133,154 Systems and methods for delivering drugs to selected locations within the body 20 2003
 
COVIDIEN LP (2)
8,529,819 Wound closure material 6 2008
* 2010/0087,840 WOUND CLOSURE MATERIAL 93 2009
 
Advanced Bio Prosthestic Surfaces, Ltd. (1)
* 8,252,044 Device for in vivo delivery of bioactive agents and method of manufacture thereof 1 2000
 
MEDTRONIC, INC. (2)
* 5,824,048 Method for delivering a therapeutic substance to a body lumen 486 1996
* 5,779,732 Method and apparatus for implanting a film with an exandable stent 60 1997
 
MASSACHUSETTS INSTITUTE OF TECHNOLOGY (6)
7,070,590 Microchip drug delivery devices 27 2000
7,918,842 Medical device with controlled reservoir opening 5 2004
7,892,221 Method of controlled drug delivery from implant device 1 2005
* 2006/0189,963 MULTI-RESERVOIR DEVICE FOR CONTROLLED DRUG DELIVERY 4 2006
7,901,397 Method for operating microchip reservoir device 1 2007
* 2008/0051,766 Method for Operating Microchip Reservoir Device 2 2007
 
MICRUS ENDOVASCULAR CORPORATION (1)
* 2008/0103,444 Method For Making A Reinforced Balloon With Composite Materials 3 2008
 
MEDTRONIC AVE, INC. (1)
6,206,915 Drug storing and metering stent 167 1998
 
BIOSENSORS INTERNATIONAL GROUP, LTD. (19)
7,682,387 Drug-delivery endovascular stent and method for treating restenosis 5 2003
* 2004/0030,380 Drug-delivery endovascular stent and method for treating restenosis 61 2003
7,727,275 Drug-delivery endovascular stent and method of forming the same 29 2004
* 2005/0038,505 Drug-delivery endovascular stent and method of forming the same 73 2004
7,901,451 Drug-delivery endovascular stent and method for treating restenosis 0 2005
* 2006/0069,427 Drug-delivery endovascular stent and method for treating restenosis 56 2005
* 2007/0173,923 Drug reservoir stent 78 2006
* 2006/0229,706 Drug-Delivery Endovascular Stent and Method for Treating Restenosis 38 2006
8,067,055 Drug-delivery endovascular stent and method of use 0 2007
* 2008/0097,568 DRUG-DELIVERY ENDOVASCULAR STENT AND METHOD OF USE 11 2007
* 2008/0103,584 Temporal Intraluminal Stent, Methods of Making and Using 19 2007
* 2008/0097,591 DRUG-DELIVERY ENDOVASCULAR STENT AND METHOD OF USE 18 2007
8,252,046 Drug-delivery endovascular stent and method for treating restenosis 1 2009
8,308,795 Drug-delivery endovascular stent and method of forming the same 0 2010
* 2010/0312,328 DRUG-DELIVERY ENDOVASCULAR STENT AND METHOD OF FORMING THE SAME 1 2010
8,252,047 Drug-delivery endovascular stent and method for treating restenosis 0 2011
8,871,292 Drug-delivery endovascular stent and method for treating restenosis 0 2012
8,545,550 Drug-delivery endovascular stent and method for treating restenosis 0 2012
8,715,341 Drug-delivery endovascular stent and method of forming the same 0 2012
 
COOK MEDICAL TECHNOLOGIES LLC (13)
* 7,550,005 Coated implantable medical device 17 2002
* 2003/0028,243 Coated implantable medical device 292 2002
8,172,793 Coated medical device 3 2005
* 2005/0278,021 Coated medical device 103 2005
* 2006/0020,331 Coated medical device 57 2005
* 2006/0195,176 Coated implantable medical device 13 2006
* 8,758,428 Coated implantable medical device 0 2007
* 2008/0147,166 COATED IMPLANTABLE MEDICAL DEVICE 2 2007
8,673,387 Coated medical device 5 2009
* 2009/0136,560 COATED MEDICAL DEVICE 39 2009
* 8,945,206 Methods for making implantable medical devices 0 2009
* 2009/0285,975 METHODS FOR MAKING IMPLANTABLE MEDICAL DEVICES 4 2009
8,974,522 Coated medical device 0 2011
 
Radiance Medical Systems, Inc. (1)
* 6,090,136 Self expandable tubular support 80 1997
 
PERCUSURGE, INC. (1)
* 6,554,795 Balloon catheter and method of manufacture 28 1998
 
GENESIS MICROCHIP INC. (2)
7,445,766 Medical device and method for diagnostic sensing 5 2006
* 2006/0171,888 Medical Device and Method for Diagnostic Sensing 1 2006
 
MAYO FOUNDATION FOR MEDICAL EDUCATION AND RESEARCH (3)
8,465,453 Kits, apparatus and methods for magnetically coating medical devices with living cells 0 2006
* 2006/0286,137 Kits, apparatus and methods for magnetically coating medical devices with living cells 3 2006
* 2011/0118,820 MAGNETIC MEDICAL APPARATUS, KITS, AND METHODS 0 2011
 
C.R. BARD, INC. (1)
* 2012/0041,419 TRIMMABLE CATHETER INCLUDING DISTAL PORTION STABILITY FEATURES 0 2011
 
ENDOLOGIX, INC. (1)
* 2010/0261,662 UTILIZATION OF MURAL THROMBUS FOR LOCAL DRUG DELIVERY INTO VASCULAR TISSUE 8 2010
 
WYETH (19)
8,029,561 Drug combination useful for prevention of restenosis 2 2000
6,776,796 Antiinflammatory drug and delivery device 135 2001
7,261,735 Local drug delivery devices and methods for maintaining the drug coatings thereon 61 2001
8,303,609 Coated medical devices 0 2001
* 2002/0133,183 Coated medical devices 185 2001
7,195,640 Coated medical devices for the treatment of vulnerable plaque 77 2002
* 2003/0060,877 Coated medical devices for the treatment of vascular disease 85 2002
7,108,701 Drug releasing anastomosis devices and methods for treating anastomotic sites 210 2002
* 2003/0065,346 Drug releasing anastomosis devices and methods for treating anastomotic sites 32 2002
7,056,550 Medical devices, drug coatings and methods for maintaining the drug coatings thereon 35 2003
* 2004/0102,758 Medical devices, drug coatings and methods for maintaining the drug coatings thereon 14 2003
7,300,662 Drug/drug delivery systems for the prevention and treatment of vascular disease 18 2004
8,236,048 Drug/drug delivery systems for the prevention and treatment of vascular disease 0 2004
* 2005/0033,261 Drug/drug delivery systems for the prevention and treatment of vascular disease 6 2004
* 2004/0243,097 Antiproliferative drug and delivery device 8 2004
8,182,527 Heparin barrier coating for controlled drug release 1 2004
* 2005/0004,663 Heparin barrier coating for controlled drug release 104 2004
* 2006/0235,503 Local drug delivery devices and methods for maintaining the drug coatings thereon 2 2006
* 2007/0087,028 INTRALUMINAL DEVICES FOR THE PREVENTION AND TREATMENT OF VASCULAR DISEASE 1 2006
 
ANGIOSCORE, INC. (10)
7,955,350 Apparatus and methods for treating hardened vascular lesions 14 2004
* 2004/0243,158 Apparatus and methods for treating hardened vascular lesions 26 2004
8,080,026 Apparatus and methods for treating hardened vascular lesions 8 2004
* 2005/0021,071 Apparatus and methods for treating hardened vascular lesions 22 2004
* 2006/0259,005 Methods and systems for delivering substances into luminal walls 18 2006
* 2009/0105,687 SCORING CATHETER WITH DRUG DELIVERY MEMBRANE 30 2008
8,454,636 Apparatus and methods for treating hardened vascular lesions 0 2011
9,173,977 Coating formulations for scoring or cutting balloon catheters 0 2012
8,864,743 Methods and systems for delivering substances into luminal walls 0 2012
8,721,667 Apparatus and methods for treating hardened vascular lesions 0 2013
 
SUN BIOMEDICAL, LTD. (1)
* 2004/0024,450 Drug-delivery endovascular stent and method for treating restenosis 52 2003
 
DURECT CORPORATION (5)
6,629,969 Catheter for modification of agent formulation 13 2001
7,250,043 Catheter for modification of agent formulation 4 2003
* 2004/0068,251 Catheter for modification of agent formulation 4 2003
7,819,855 Catheter for modification of agent formulation 0 2007
* 2007/0185,473 Catheter for modification of agent formulation 0 2007
 
CESCO BIOENGINEERING CO., LTD. (1)
* 2006/0292,690 Method of making cell growth surface 26 2006
 
BOSTON SCIENTIFIC SCIMED, INC. (33)
* 5,972,027 Porous stent drug delivery system 402 1997
6,280,411 Localized delivery of drug agents 190 1998
* 6,253,443 Method of forming a stent 198 1999
6,458,152 Coiled sheet graft for single and bifurcated lumens and methods of making and use 68 2000
6,964,676 Stent securement system 21 2000
6,939,320 Localized delivery of drug agents 111 2001
* 6,793,672 Coiled sheet graft for single and bifurcated lumens and methods of making and use 23 2002
* 2002/0193,864 Coiled sheet graft for single and bifurcated lumens and methods of making and use 18 2002
* 2005/0060,020 Covered stent with biologically active material 148 2003
7,041,130 Stent for controlled release of drug 95 2004
* 2004/0260,391 Stent for controlled release of drug 9 2004
* 8,092,513 Coiled sheet graft for single and bifurcated lumens and methods of making and use 1 2004
* 2005/0004,654 Coiled sheet graft for single and bifurcated lumens and methods of making and use 15 2004
8,177,743 Localized delivery of drug agents 0 2005
* 2005/0182,361 Localized delivery of drug agents 54 2005
* 2006/0217,798 Stent having active release reservoirs 4 2006
7,963,990 Stent drug delivery system 1 2008
* 2008/0288,059 Stent Drug Delivery System 1 2008
8,114,049 Balloon catheter devices with folded balloons 2 2009
* 2009/0227,949 BALLOON CATHETER DEVICES WITH FOLDED BALLOONS 51 2009
* 2009/0227,948 BALLOON CATHETER DEVICES WITH SHEATH COVERING 39 2009
* 2010/0272,773 Use of Drug Polymorphs to Achieve Controlled Drug Delivery From a Coated Medical Device 22 2010
* 2011/0008,260 Use of Nanocrystals for Drug Delivery from a Balloon 5 2010
* 8,617,136 Balloon catheter devices with drug delivery extensions 0 2010
* 2011/0054,443 BALLOON CATHETER DEVICES WITH DRUG DELIVERY EXTENSIONS 7 2010
* 2011/0054,396 Balloon Catheter Devices With Drug-Coated Sheath 31 2010
8,262,613 Localized delivery of drug agents 1 2011
* 2011/0270,226 BALLOON CATHETER DEVICES WITH SHEATH COVERING 0 2011
8,889,211 Coating process for drug delivery balloons using heat-induced rewrap memory 0 2011
9,056,152 Medical device with crystalline drug coating 0 2011
8,669,360 Methods of converting amorphous drug substance into crystalline form 0 2011
* 2013/0018,448 DRUG ELUTION MEDICAL DEVICE 4 2012
8,574,191 Localized delivery of drug agents 0 2012
 
EBARA TECHNOLOGIES, INC. (2)
7,971,333 Manufacturing process for polymetric stents 54 2006
* 2007/0283,552 Manufacturing process for polymeric stents 39 2006
 
HORIZON TECHNOLOGY FUNDING COMPANY LLC (1)
7,008,397 Cardiac implant and methods 14 2002
* Cited By Examiner