Retroviral protease inhibitors

Number of patents in Portfolio can not be more than 2000

United States of America Patent

PATENT NO 5708004
SERIAL NO

08450605

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ATTORNEY / AGENT: (SPONSORED)

Importance

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Abstract

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Hydroxyethylamine compounds are effective as retroviral protease inhibitors, and in particular as inhibitors of HIV protease.

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First Claim

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Family

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Patent Owner(s)

Patent OwnerAddressTotal Patents
MONSANTO COMPANYST LOUIS, MO292

International Classification(s)

Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Reed, Kathryn L Raleigh, NC 26 166
Talley, John J Chesterfield, MO 228 2159

Cited Art Landscape

Patent Info (Count) # Cites Year
 
Other [Check patent profile for assignment information] (1)
* H725 Ureido amino and imino acids, compositions and methods for use 133 1987
 
MERCK & CO., INC. (1)
* 4668770 Renin inhibitory tripeptides 155 1984
 
ABBOTT LABORATORIES (2)
* 4977277 Functionalized peptidyl aminodiols and -triols 4-amino-5-cyclohexyl-3-hydroxy-1,2-oxopentane and derivatives thereof 135 1989
* 5151438 Retroviral protease inhibiting compounds 24 1991
 
SANKYO COMPANY, LIMITED (1)
* 4548926 Hypotensive peptides and their use 162 1984
 
Merck & Co., Ltd. (1)
* 4477441 Renin inhibitors containing a C-terminal disulfide cycle 148 1983
 
HOFFMANN-LA ROCHE INC. (1)
* 5157041 Amino acid derivatives 100 1989
 
E. R. Squibb & Sons, Inc. (4)
* 4514391 Hydroxy substituted peptide compounds 143 1983
* 4616088 Amino acid ester and amide renin inhibitor 153 1984
* 4749781 Aminocarbonyl renin inhibitors 3 1986
* 4757050 Ureido renin inhibitors 136 1987
 
UPJOHN COMPANY, THE (1)
* 5132400 Peptides containing a (1-amino-2-hydroxy-2-heterocyclic)ethyl moiety 27 1990
 
FUJISAWA PHARMACEUTICAL CO., LTD. (1)
* 4963530 Renin inhibitor peptide compounds, a process for the preparation thereof and pharmaceutical composition comprising the same 139 1988
 
PFIZER INC. (2)
* 4668769 Oxa- and azahomocyclostatine polypeptides 143 1985
* 4599198 Intermediates in polypeptide synthesis 158 1985
* Cited By Examiner

Patent Citation Ranking

Forward Cite Landscape

Patent Info (Count) # Cites Year
 
Elan Pharmaceuticals and pharmacia & Upjohn Company LLC (1)
* 2007/0213,407 Compounds to treat Alzheimer's disease 4 2006
 
Alzheimer's Collaboration (1)
* 2009/0074,746 Compounds to treat alzheimer's disease 0 2004
 
PHARMACIA CORPORATION (1)
6538006 Retroviral protease inhibitors 1 2001
 
ELAN PHARMACEUTICALS, INC. (10)
7119085 Methods to treat alzheimer's disease 0 2001
6737420 Compounds to treat Alzheimer's disease 5 2001
7034182 Compounds to treat Alzheimer's disease 10 2001
6992081 Compounds to treat Alzheimer's disease 0 2001
6982264 Substituted alcohols useful in treatment of Alzheimer's disease 15 2002
7030239 Compounds to treat Alzheimer's disease 0 2004
* 2004/0214,846 Compounds to treat Alzheimer's disease 1 2004
7553831 Compounds to treat Alzheimer's disease 0 2005
7432389 Compounds for the treatment of Alzheimer's disease 0 2006
* 2006/0276,642 Compounds to treat Alzheimer's disease 0 2006
 
PHARMACIA & UPJOHN COMPANY (8)
7214715 Compounds to treat Alzheimer's disease 5 2001
6846813 Compounds to treat alzheimer's disease 5 2001
* 2002/0143,177 Compounds to treat alzheimer's disease 6 2001
7244755 Hydroxypropylamines 20 2002
7338965 3,4-disubstituted, 3,5-disubstituted and 3,4,5-substituted piperidines 4 2002
* 2004/0034,031 3,4-Disubstituted, 3,5-disubstituted and 3,4,5-substituted piperidines 0 2002
7262208 Hydroxypropyl amides for the treatment of Alzheimer's disease 1 2003
* 2004/0039,034 Hydroxypropyl amides for the treatment of Alzheimer's disease 0 2003
 
G. D. Searle & Co. (1)
7026333 Retroviral protease inhibitors 3 2000
* Cited By Examiner