US Patent No: 5,708,004

Number of patents in Portfolio can not be more than 2000

Retroviral protease inhibitors

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ATTORNEY / AGENT: (SPONSORED)

Importance

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Abstract

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Hydroxyethylamine compounds are effective as retroviral protease inhibitors, and in particular as inhibitors of HIV protease.

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First Claim

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all claims..

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Patent Owner(s)

Patent OwnerAddressTotal Patents
MONSANTO COMPANYST LOUIS, MO1734

International Classification(s)

Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Reed, Kathryn L Raleigh, NC 31 166
Talley, John J Somerville, MA 277 1974

Cited Art Landscape

Patent Info (Count) # Cites Year
 
E. R. Squibb & Sons, Inc. (4)
4,514,391 Hydroxy substituted peptide compounds 143 1983
4,616,088 Amino acid ester and amide renin inhibitor 153 1984
4,749,781 Aminocarbonyl renin inhibitors 3 1986
4,757,050 Ureido renin inhibitors 136 1987
 
ABBOTT LABORATORIES (2)
4,977,277 Functionalized peptidyl aminodiols and -triols 4-amino-5-cyclohexyl-3-hydroxy-1,2-oxopentane and derivatives thereof 135 1989
5,151,438 Retroviral protease inhibiting compounds 24 1991
 
PFIZER INC. (2)
4,668,769 Oxa- and azahomocyclostatine polypeptides 143 1985
4,599,198 Intermediates in polypeptide synthesis 158 1985
 
FUJISAWA PHARMACEUTICAL CO., LTD. (1)
4,963,530 Renin inhibitor peptide compounds, a process for the preparation thereof and pharmaceutical composition comprising the same 139 1988
 
HOFFMANN-LA ROCHE INC. (1)
5,157,041 Amino acid derivatives 100 1989
 
MERCK & CO., INC. (1)
4,668,770 Renin inhibitory tripeptides 155 1984
 
MERCK & CO., LTD. (1)
4,477,441 Renin inhibitors containing a C-terminal disulfide cycle 148 1983
 
SANKYO COMPANY, LIMITED (1)
4,548,926 Hypotensive peptides and their use 162 1984
 
The Upjohn Company (1)
5,132,400 Peptides containing a (1-amino-2-hydroxy-2-heterocyclic)ethyl moiety 27 1990
 
Other [Check patent profile for assignment information] (1)
H725 Ureido amino and imino acids, compositions and methods for use 133 1987

Patent Citation Ranking

Forward Cite Landscape

Patent Info (Count) # Cites Year
 
ELAN PHARMACEUTICALS, INC. (8)
7,119,085 Methods to treat alzheimer's disease 0 2001
6,737,420 Compounds to treat Alzheimer's disease 3 2001
7,034,182 Compounds to treat Alzheimer's disease 6 2001
6,992,081 Compounds to treat Alzheimer's disease 0 2001
6,982,264 Substituted alcohols useful in treatment of Alzheimer's disease 12 2002
7,030,239 Compounds to treat Alzheimer's disease 0 2004
7,553,831 Compounds to treat Alzheimer's disease 0 2005
7,432,389 Compounds for the treatment of Alzheimer's disease 0 2006
 
PHARMACIA & UPJOHN COMPANY (5)
7,214,715 Compounds to treat Alzheimer's disease 5 2001
6,846,813 Compounds to treat alzheimer's disease 2 2001
7,244,755 Hydroxypropylamines 17 2002
7,338,965 3,4-disubstituted, 3,5-disubstituted and 3,4,5-substituted piperidines 4 2002
7,262,208 Hydroxypropyl amides for the treatment of Alzheimer's disease 1 2003
 
G. D. Searle & Co. (1)
7,026,333 Retroviral protease inhibitors 3 2000
 
PHARMACIA CORPORATION (1)
6,538,006 Retroviral protease inhibitors 1 2001