Antibodies specific for Rse receptor protein tyrosine kinase

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United States of America Patent

PATENT NO 5709858
SERIAL NO

08445640

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Abstract

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The protein tyrosine kinase receptors, designated Rse and HPTK6, have been purified from human and/or murine cell tissues. Rse and HPTK6 have been cloned from a cDNA library of a human liver carcinoma cell line (i.e., Hep 3B) using PCR amplification. Provided herein are nucleic acid sequences encoding Rse and HPTK6 useful as diagnostics and in the recombinant preparation of Rse and HPTK6. Rse and HPTK6 are used in the preparation and purification of antibodies thereto and in diagnostic assays.

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Patent Owner(s)

Patent OwnerAddress
GENENTECH INCSOUTH SAN FRANCISCO CA

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Godowski, Paul J Burlingame, CA 1845 7409
Mark, Melanie R Burlingame, CA 26 357
Scadden, David T Weston, MA 67 498

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