Inhibition of neovascularization using VEGF-specific oligonucleotides

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United States of America Patent

PATENT NO 5710136
SERIAL NO

08501713

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Abstract

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Disclosed are methods of reducing neovascularization and of treating various disorders associated with neovascularization. These methods include administering to a tissue or subject a synthetic oligonucleotide specific for vascular endothelial growth factor nucleic acid effective in inhibiting the expression of vascular endothelial growth factor.

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Patent Owner(s)

Patent OwnerAddress
IDERA PHARMACEUTICALS INC167 SIDNEY STREET CAMBRIDGE MA 02139

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Robinson, Gregory S Acton, MA 22 275
Smith, Lois Elaine Hodgson West Newton, MA 3 153

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