Optical solid-phase biosensor based on polyionic layers labelled with fluorescent dyes
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United States of America Patent
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Jan 27, 1998
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app pub date -
Oct 24, 1995
filing date -
Mar 18, 1992
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Abstract
The present invention relates to an optical solid-phase biosensor for the detection of molecules which can be labelled with a fluorescent dye for the identification of substances in solution, for which there exists a biomolecule (receptor) which specifically recognises these and is chemically bonded to the uppermost layer of one or more layers of polyions on the surface of the sensor, by measurement of the Forster transfer between another dye molecule which is bonded in one of the uppermost layers of the sensor, and the said dye molecule.
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