Immunoassay elements having a receptor zone
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United States of America Patent
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Feb 3, 1998
Grant Date -
N/A
app pub date -
Jun 16, 1994
filing date -
Dec 22, 1992
priority date (Note) -
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Abstract
A dry immunoassay analytical element, for assaying a ligand is disclosed. The element comprises, in the following order, (a) a layer containing a labeled ligand, (b) a bead spreading layer, c) a cross-linked hydrophilic polymer layer and d) a support; wherein (i) a fixed concentration of an immobilized receptor for the labeled ligand is located in a zone at the interface of layers (b) and (c); and (ii) the receptors are immobilized by being covalently bonded to polymeric beads that are smaller than the beads in layer (c).
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