Method for inhibiting cellular proliferation using antisense oligonucleotides to interleukin-6 receptor mRNA
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United States of America Patent
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Feb 10, 1998
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N/A
app pub date -
Jun 7, 1995
filing date -
Jun 7, 1995
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Expired
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Abstract
The present invention relates to methods of treating disease-associated cellular proliferation using oligonucleotides. In particular, it relates to the use of oligonulceotides which are substantially complementary to interleukin-6 receptor mRNA sequences. In the form of pharmaceutical compositions, these oligonucleotides are suitable for administration to human subjects for the treatment of abnormal cellular proliferation due to such diseases as cancer, autoimmune disorders and viral infection.
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