Inhibition of adherence of microorganisms to biomaterial surfaces by treatment with carbohydrates
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United States of America Patent
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Feb 17, 1998
Grant Date -
N/A
app pub date -
May 24, 1995
filing date -
Nov 9, 1993
priority date (Note) -
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Abstract
A method of inhibiting adherence of bacteria, fungus and other similar microorganisms to the surface of biomaterials is disclosed wherein biomaterials such as catheters and prosthetic devices are pretreated with a coating of a simple carbohydrate such as a mono- or di-saccharide. Intravascular catheters treated as such are shown to have significant reduction of adherence by S. epidermidis, S. aureus, Candidas and other organisms associated with nosocomial infection.
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