Monoclonal antibody to prostate-derived acid phosphatase and method for determination of acid phosphatase using the same as well as kit for determination
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United States of America Patent
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Feb 17, 1998
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N/A
app pub date -
Jan 26, 1995
filing date -
Jul 11, 1991
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Abstract
According to the present invention, there are provided a monoclonal antibody to prostate-derived acid phosphatase and a method for determination of prostate-derived acid phosphatase using the monoclonal antibody. Prostate-derived acid phosphatase is boostered in animal and spleen cells isolated from the animal are fused with myeloma cells. The hybridoma capable of producing a monoclonal antibody having extremely high specificity to prostate-derived acid phosphatase is subjected to cloning. Using the monoclonal antibody produced by the hybridoma, prostate-derived acid phosphatase in a sample can be detected with extremely high sensitivity.
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