Ultrashort pulse high repetition rate laser system for biological tissue processing

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United States of America Patent

PATENT NO 5720894
SERIAL NO

08584522

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Abstract

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A method and apparatus is disclosed for fast, efficient, precise and damage-free biological tissue removal using an ultrashort pulse duration laser system operating at high pulse repetition rates. The duration of each laser pulse is on the order of about 1 fs to less than 50 ps such that energy deposition is localized in a small depth and occurs before significant hydrodynamic motion and thermal conduction, leading to collateral damage, can take place. The depth of material removed per pulse is on the order of about 1 micrometer, and the minimal thermal and mechanical effects associated with this ablation method allows for high repetition rate operation, in the region 10 to over 1000 Hertz, which, in turn, achieves high material removal rates. The input laser energy per ablated volume of tissue is small, and the energy density required to ablate material decreases with decreasing pulse width. The ablation threshold and ablation rate are only weakly dependent on tissue type and condition, allowing for maximum flexibility of use in various biological tissue removal applications. The use of a chirped-pulse amplified Titanium-doped sapphire laser is disclosed as the source in one embodiment.

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Patent Owner(s)

Patent OwnerAddress
LAWRENCE LIVERMORE NATIONAL SECURITY LLC7000 EAST AVENUE LIVERMORE CA 94550

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Da, Silva Luiz B Danville, CA 67 6296
Feit, Michael D Livermore, CA 5 480
Glinsky, Michael E Livermore, CA 2 458
Matthews, Dennis L Moss Beach, CA 13 1123
Neev, Joseph Laguna Beach, CA 33 2190
Perry, Michael D Livermore, CA 29 1565
Rubenchik, Alexander M Livermore, CA 34 1832
Stuart, Brent C Fremont, CA 15 1092

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