Non-crosslinked protein particles for therapeutic and diagnostic use
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United States of America Patent
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Mar 10, 1998
Grant Date -
N/A
app pub date -
Jun 6, 1995
filing date -
Jan 15, 1991
priority date (Note) -
Expired
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Abstract
Albumin particles in the nanometer and micrometer size range in an aqueous suspension are rendered stable against resolubilization without the aid of a crosslinking agent and without denaturation, by the incorporation of a stabilizing agent in the particle composition. Particles which are primarily albumin in the nanometer and micrometer size range in an aqueous suspension are rendered stable against resolublization by the incorporation of a reducing agent, oxidizing agent, hydrogen-accepting molecule, high molecular weight polymer, sulfur-containing ring compound or combinations thereof.
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