Rapid, high capacity nucleic acid based assay
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United States of America Patent
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Mar 10, 1998
Grant Date -
N/A
app pub date -
Apr 21, 1994
filing date -
Mar 31, 1992
priority date (Note) -
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Abstract
A rapid, high capacity method using chaotropic agents for evaluating nucleic acids is described. Samples containing the target nucleic acid can be evaluated in a nucleic acid based sandwich hybridization assay which is performed, in part, in a chaotropic solution which is removed prior to detecting and/or quantitating the product. This assay can be used to detect and/or quantitate nucleic acid levels. It can also be used as an infectivity assay and/or as an assay to evaluate anti-infectious agent activity of compounds.
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