Syndecan stimulation of cellular differentiation

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United States of America Patent

PATENT NO 5726058
SERIAL NO

08472217

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Abstract

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Methods are provided for altering levels of syndecan within a cell. The methods include enhancing syndecan expression via administration of growth factors, preventing suppression of syndecan expression via administration of anti-steroid agents, and altering syndecan biochemistry within the cell. The methods are used to induce or maintain cellular differentiation, and to decrease the growth of malignant cells. Application of the methods to the treatment of patients, including humans, is provided.

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Patent Owner(s)

Patent OwnerAddress
BIOTIE THERAPIES LTDTURKU TURKU WESTERN FINLAND

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Alanen-Kurki, Leena Piispankatu 6-E-31, Fin-20500 Turku, FI 1 16
Auvinen, Petri Kirschgartenstrasse 5, 69126 Heidelberg, DE 5 16
Jaakkola, Panu Kellonsoittajankatu 13 B 20, FIN 20500 Turku, FI 4 20
Jalkanen, Markku Rauvolantie 79, FIN-20760 Piispanristi, FI 24 65
Leppa, Sirpa Valkintie 14056, Fin 20660 Littoinen, FI 1 16
Mali, Markku Inkereentie 176, FIN-24280 Salo, FI 1 16
Vihinen, Tapani Kasenkatu 11 C 54, FIN 20700, FI 3 19
Warri, Anni Johaninkuja 2 AS 2, 21420 Lieto, FI 11 59

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