2,5-diamino-3,4-disubstituted-1,6-diphenylhexane isosteres comprising benzamide, sulfonamide and anthranilamide subunits and methods of using same

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United States of America Patent

PATENT NO 5728718
SERIAL NO

08359612

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Abstract

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The present invention provides 2,5-diamino-3,4-disubstituted-1,6-diphenylhexane (DAD) isosteres comprising benzamide, sulfonamide and anthranilamide subunits, a pharmaceutical composition comprising such compounds, a method of using such compounds to treat retroviral, specifically HIV and more specifically HIV-1 and HIV-2, infections in mammals, particularly humans, a method of synthesizing asymmetric DAD isosteres comprising benzamide, sulfonamide and anthranilamide subunits, and a method of using such compounds to assay new compounds for antiretroviral activity.

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Patent Owner(s)

Patent OwnerAddress
HEALTH AND HUMAN SERVICES DEPARTMENT OF UNITED STATES OF AMERICA THE AS REPRESENTED BY THE SECRETARYC/O CENTERS FOR DISEASE CONTROL AND PREVENTION OFFICE OF TECHNOLOGY TRANSFER EXECUTIVE PARK BUILDING 4 SUITE 1103 ATLANTA GA 30329

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Erickson, John W Frederick, MD 79 945
Randad, Ramnarayan S Frederick, MD 6 33

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