Bonding bio-active materials to substrate surfaces

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United States of America Patent

PATENT NO 5728751
SERIAL NO

08755187

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Abstract

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A medical device having a bio-active coating is prepared by providing a polymeric substrate having hydroxyl and/or amine functionality on a surface thereof and applying the bio-active coating to the surface. The bio-active coating is the reaction product of two different reactions. The first reaction includes reacting the polymeric substrate with a hydrophilic, isocyanate-terminated spacer having at least one isocyanate group at its first and second ends. The second reaction includes reacting a remaining, unreacted isocyanate-terminated end of the spacer with a bio-active agent to bond the bio-active agent to the spacer.

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Patent Owner(s)

Patent OwnerAddress
BOSTON SCIENTIFIC SCIMED INCONE SCIMED PLACE MAPLE GROVE MN 55311-1566

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Patnaik, Birendra K Chester, NJ 18 1153

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