High affinity TGF.beta. nucleic acid ligands and inhibitors
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United States of America Patent
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Mar 24, 1998
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N/A
app pub date -
Jun 2, 1995
filing date -
Jun 11, 1990
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Expired
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Abstract
Methods are described for the identification and preparation of high-affinity nucleic acid ligands to TGF.beta.. Included in the invention are specific RNA and ssDNA ligands to TGF.beta.1 identified by the SELEX method. Also included are RNA ligands that inhibit the interaction of TGF.beta.1 with its receptor.
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