Enhancement of oligonucleotide inhibition of protein production, cell proliferation and / or multiplication of infectious disease pathogens

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United States of America Patent

PATENT NO 5739309
SERIAL NO

08453046

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Abstract

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The invention features the use of a purified first targeted oligonucleotide in combination with either 1) a subtargeted oligonucleotide, 2) second targeted oligonucleotide, or 3) a non-targeted phosphorothioate oligonucleotide, to inhibit protein production of a targeted nucleic acid sequence, cell proliferation, and/or the multiplication of a foreign organism. The subtargeted oligonucleotide contains a truncated version of the targeted oligonucleotide.

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Patent Owner(s)

Patent OwnerAddress
GEN-PROBE INCORPORATED10210 GENETIC CENTER DRIVE ATTN PATENT DEPT SAN DIEGO CA 92121
BIOLUCENT LLC250 CAMPUS DRIVE MARLBOROUGH MA 01752
CYTYC CORPORATION250 CAMPUS DRIVE MARLBOROUGH MA 01752
HOLOGIC INC250 CAMPUS DRIVE MARLBOROUGH MA 01752
SUROS SURGICAL SYSTEMS INC6100 TECHNOLOGY CENTER DRIVE NORTHWEST TECHNOLOGY CENTER INDIANAPOLIS IN 46278
THIRD WAVE TECHNOLOGIES INC250 CAMPUS DRIVE MARLBOROUGH MA 01752
CYTYC SURGICAL PRODUCTS LIMITED PARTNERSHIP250 CAMPUS DRIVE MARLBOROUGH MA 01752

International Classification(s)

Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Dattagupta, Nanibhushan San Diego, CA 70 2766
Kacian, Daniel L San Diego, CA 64 3002
Sridhar, C Nagaraja Simi Valley, CA 13 267

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