Methods for detecting colon cancer from stool samples
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United States of America Patent
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Apr 21, 1998
Grant Date -
N/A
app pub date -
Aug 14, 1996
filing date -
Jan 30, 1996
priority date (Note) -
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Abstract
The present invention provides methods for screening for the presence of a subpopulation of cancerous or precancerous cells in a heterogeneous cellular sample, such as a stool sample. The methods take advantage of the recognition that cellular debris from cancerous and precancerous cells is deposited onto only a longitudinal stripe of stool as the stool is forming in the colon. Accordingly, methods of the invention comprise obtaining a representative sample, such as a cross-sectional sample of stool in order to ensure that any cellular debris that is shed by colonic cells is obtained in the sample.
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