Arrays of materials attached to a substrate

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United States of America Patent

PATENT NO 5744305
SERIAL NO

08466632

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Abstract

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A synthetic strategy for the creation of large scale chemical diversity. Solid-phase chemistry, photolabile protecting groups, and photolithography are used to achieve light-directed spatially-addressable parallel chemical synthesis. Binary masking techniques are utilized in one embodiment. A reactor system, photoremovable protective groups, and improved data collection and handling techniques are also disclosed. A technique for screening linker molecules is also provided.

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Patent Owner(s)

Patent OwnerAddress
AFFYMETRIX INC A CORP OF DE3380 CENTRAL EXPRESSWAY SANTA CLARA CA 95051

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Fodor, Stephen PA Palo Alto, CA 145 8792
Pirrung, Michael C Durham, NC 60 10309
Read, J Leighton Palo Alto, CA 41 9222
Stryer, Lubert Stanford, CA 73 12071

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