Biocompatible adhesive compositions
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United States of America Patent
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Apr 28, 1998
Issued Date -
N/A
app pub date -
May 8, 1997
filing date -
Nov 21, 1988
priority date (Note) -
Expired
status (Latency Note)
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Abstract
Collagen-based compositions useful in the attachment of tissues, or the attachment of tissues to synthetic implant materials, are disclosed. The compositions comprise collagen crosslinked using a multifunctionally activated synthetic hydrophilic polymer. A particularly preferred composition comprises fibrillar collagen, a fiber disassembly agent, and a multifunctionally activated synthetic hydrophilic polymer. Methods are disclosed for using the compositions to effect the attachment of a native tissue to the surface of another native tissue, a non-native tissue, or a synthetic implant. Also disclosed are methods of using the compositions to prevent the formation of surgical adhesions.
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