Methods and materials for the induction of T cell anergy
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United States of America Patent
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May 5, 1998
Issued Date -
N/A
app pub date -
Feb 18, 1994
filing date -
Jul 9, 1992
priority date (Note) -
Expired
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Abstract
Anti-B7-1 antibodies or other B7-1 ligands may be used to prevent or treat a T-cell-mediated immune system disease in a patient or to induce antigen-specific tolerance. The anti-B7-1 antibodies may be used to cause T cell anergy, treat allograft transplant rejection, treat graft versus host disease, and prevent or treat rheumatoid arthritis. An immunosuppressive agent is co-administered with the antibody.
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