Prolonged local anesthesia with colchicine
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United States of America Patent
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May 5, 1998
Grant Date -
N/A
app pub date -
Mar 26, 1996
filing date -
Mar 26, 1996
priority date (Note) -
Expired
status (Latency Note)
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Abstract
A formulation for inducing sustained regional local anesthesia in a patient comprising a substrate comprising a local anesthetic and an effective amount of a biocompatible, biodegradable, controlled release material prolonging the release of the local anesthetic from the substrate to obtain a reversible nerve blockade when implanted or injected in a patient, and an amount of colchicine effective to prolong the duration of the local anesthesia for a time period longer than that obtainable from the substrate without colchicine.
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