Delivery of nucleotides into organisms by electroporation
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United States of America Patent
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May 12, 1998
Issued Date -
N/A
app pub date -
Jun 6, 1995
filing date -
Jan 21, 1988
priority date (Note) -
Expired
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Abstract
A method for delivering a nucleotide into an organism includes applying a composition which includes a nucleotide component to epidermis of the organism. The epidermis is electroporated, whereby at least a portion of the composition enters or passes across the epidermis, thereby delivering the nucleotide into the organism. An example of a suitable nucleotide which can be delivered by the method of the invention includes antisense oligodeoxynucleotides for treatment of melanomas.
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