Syringe and method for lyophilizing and reconstituting injectable medication
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United States of America Patent
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-
May 19, 1998
Issued Date -
N/A
app pub date -
Apr 8, 1996
filing date -
Jan 25, 1994
priority date (Note) -
In Force
status (Latency Note)
Importance
Abstract
A syringe assembly includes a substantially cylindrical syringe barrel and a plunger stopper. Distal portions on the plunger stopper are configured to permit outflow of vapor from the syringe barrel during a lyophilization process. Proximal portions of the plunger stopper are dimensioned to engage the syringe barrel in sliding fluid-tight engagement. Liquid medication in the chamber is lyophilized and a vacuum is applied to the syringe barrel after lyophilization. The plunger stopper then is urged distally into sealing engagement with the syringe barrel. A plunger rod can be engaged with the plunger stopper. The tip cap is then removed and a diluent is drawn into the chamber by moving the plunger rod and the plunger stopper in a proximal direction. The syringe assembly then can be used in the standard manner.
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