Neural regeneration using human bone morphogenetic proteins

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United States of America Patent

PATENT NO 5756457
SERIAL NO

08435120

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Abstract

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Methods and devices are disclosed for inducing growth of neural cells, and repairing neural defects in a mammal. The method comprises administering to said mammal at the site of neural defect, damage or depletion, an effective amount of a bone morphogenetic protein, either in admixture with a pharmaceutically acceptable vehicle, or adsorbed to a suitable matrix. The device comprises bone morphogenetic protein, optionally in combination with other factors, adsorbed on a suitable matrix and contained within an artificial nerve replacement vessel.

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Patent Owner(s)

  • GENETICS INSTITUTE, INC.;GENETICS INSTITUTE, LLC;THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
D'Alessandro, Josephine S Marblehead, MA 4 209
Toriumi, Dean M Riverside, IL 4 182
Wang, Elizabeth A Carlisle, MA 34 2253

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