Antibiotic formulation and use for drug resistant infections
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United States of America Patent
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Jun 2, 1998
Grant Date -
N/A
app pub date -
Jun 23, 1993
filing date -
May 11, 1993
priority date (Note) -
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Abstract
A liposomal aminoglycoside formulation comprising a neutral lipid, a negatively charged lipids and a sterol. The formulation contains unilamellar vesicles having an average size below 100 nm. A process of making liposomes containing an aminoglycoside is provided where the hydration temperature is significantly below the transition temperature of the formulation. A method for the treatment of drug susceptible and drug resistant bacteria.
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