Tandem synthetic HIV-1 peptides

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United States of America Patent

PATENT NO 5759769
SERIAL NO

08460602

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Abstract

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Novel synthetic peptides are provided which are candidate vaccines against HIV-1 and which are useful in diagnostic application. The peptides comprise an amino acid sequence of a T-cell epitope of the gag protein of HIV-1, specifically p24E linked directly to an amino acid sequence of a B-cell epitope of the V3 loop protein of an HIV-1 isolate and containing the sequence GPGR, and/or the gp41 containing the sequence ELKDWA. Multimeric forms of the tandem synthetic peptides are provided.

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Patent Owner(s)

Patent OwnerAddress
CONNAUGHT LABORATORIES LIMITEDNORTH YORK

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Chong, Pele Richmond Hill, CA 74 753
Klein, Michel H Willowdale, CA 151 1252
Sia, Charles D Y Thornhill, CA 12 125

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