Cellular apoptosis susceptibility protein (CSP) and antisense CSP

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United States of America Patent

PATENT NO 5759782
SERIAL NO

08480662

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Abstract

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The cDNA and amino acid sequences for a cellular apoptosis susceptibility (CAS) protein are used to detect expression and amplification of the CAS gene in normal and cancer cells. An antisense CAS gene sequence introduced into living cells inhibits CAS protein activity and thus prevents or inhibits apoptosis in the cells.

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Patent Owner(s)

Patent OwnerAddress
HEALTH AND HUMAN SERVICES DEPARTMENT OF UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARYBETHESDA MD 20892

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Brinkmann, Ulrich Kensington, MD 116 1819
Pastan, Ira Potomac, MD 66 1404

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