Production of platelet derived growth factor (PDGF) an muteins thereof

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United States of America Patent

PATENT NO 5759815
SERIAL NO

07686550

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Abstract

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Native, analog, and mutein species of A and B chains of platelet derived growth factor are produced in prokaryotes, purified, combined, and modified in vitro to produce various active AA, AB, and BB PDGF dimers.

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Patent Owner(s)

Patent OwnerAddress
CREATIVE BIOMOLECULES INCHOPKINTON MASSACHUSETTS 01478

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Babickas, Zita A Natick, MA 1 18
Charette, Marc F West Roxbury, MA 18 343
Oppermann, Hermann Medway, MA 112 3953

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