Peralkylated oligopeptide mixtures

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United States of America Patent

PATENT NO 5763193
SERIAL NO

08577846

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Abstract

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Linear C.sub.1 -C.sub.7 -alkyl peralkylated oligopeptide sets of molecules are disclosed, as are their methods of synthesis and use in acceptor binding assays. Each molecule or chain of a set contains the same number of two to about ten substituted C.sub.1 -C.sub.7 -alkyl peralkylated amino acid residues, and the member chains of a set are present in equimolar amounts. The chains of a set contain one or more predetermined peralkylated amino acid residues at one or more predetermined positions of the peralkylated oligopeptide chain. The set contains equimolar amounts of at least six different peralkylated amino acid residues at one or more of the same predetermined positions of the peralkylated oligopeptide chain. Libraries of such sets, processes for their use and solid support-linked peralkylated sets are also contemplated, as are specific permethylated oligopeptides.

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Patent Owner(s)

Patent OwnerAddress
LION BIOSCIENCE AGHEIDELBERG

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Blondelle, Sylvie La Jolla, CA 7 139
Houghten, Richard A Solana Beach, CA 84 1963
Ostresh, John M Encinitas, CA 27 500

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