DNA encoding a cytokine that induces apoptosis
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United States of America Patent
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Jun 9, 1998
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N/A
app pub date -
Jun 25, 1996
filing date -
Jun 29, 1995
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Abstract
A novel cytokine designated TRAIL induces apoptosis of certain target cells, including cancer cells and virally infected cells. Isolated DNA sequences encoding TRAIL are disclosed, along with expression vectors and transformed host cells useful in producing TRAIL polypeptides. Antibodies that specifically bind TRAIL are provided as well.
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