Oral drug delivery compositions and methods
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United States of America Patent
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Jun 16, 1998
Issued Date -
N/A
app pub date -
Oct 23, 1995
filing date -
Apr 22, 1993
priority date (Note) -
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Abstract
The present invention relates to an oral drug delivery system, and in particular to modified amino acids and modified amino acid derivatives for use as a delivery system of sensitive agents such as bioactive peptides. The modified amino acids and derivatives can form non-covalent mixtures with active biological agents and in an alternate embodiment can releasably carry active agents. Modified amino acids can also form drug containing microspheres. These mixtures are suitable for oral administration of biologically active agents to animals. Methods for the preparation of such amino acids are also disclosed.
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