US Patent No: 5,769,899

Number of patents in Portfolio can not be more than 2000

Cartilage repair unit

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ATTORNEY / AGENT: (SPONSORED)
 

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Abstract

A bio-absorbable cartilage repair system for regenerating damaged or destroyed articular cartilage on the surface of a bone by establishing a chondrogenic growth-supporting matrix between an area of removed damaged or destroyed articular cartilage and the adjacent healthy cancellous bone. The system is at least one assembly of a bio-absorbable delivery unit, configured and dimensioned to be mounted in both the removed area and the adjacent healthy area, and a porous bio-absorbable insert supported by and in the delivery unit and establishing communication between the removed area and the adjacent healthy area for a chondrogenic growth-supporting matrix. The insert preferably includes a repair factor (e.g., a growth factor, an attachment factor, or both) releasably disposed in the insert to assist in establishing the chondrogenic growth-supporting matrix.

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First Claim

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Patent Owner(s)

Patent OwnerAddressTotal Patents
DEPUY ORTHOPAEDICS, INC.WARSAW, IN405
NORTH SHORE UNIVERSITY HOSPITAL RESEARCH CORPORATIONMANHASSET, NY11

International Classification(s)

  • [Classification Symbol]
  • [Patents Count]

Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Grande, Jr Daniel Anthony Seacliff, NY 1 232
Schwartz, Robert Elliott Old Westbury, NY 1 232

Cited Art

Patent Info (Count) # Cites Year
 
REGEN CORPORATION (2)
4,880,429 Prosthetic meniscus 163 1987
5,306,311 Prosthetic articular cartilage 267 1991
 
ADVANCED BIOHEALING, INC. (1)
4,963,489 Three-dimensional cell and tissue culture system 202 1988
 
BAXTER INTERNATIONAL INC. (1)
4,627,853 Method of producing prostheses for replacement of articular cartilage and prostheses so produced 206 1985
 
BIOCON OY (1)
5,084,051 Layered surgical biocomposite material 172 1988
 
DEPUY ORTHOPAEDICS, INC. (1)
5,123,927 Method and apparatus for antibiotic knee prothesis 54 1991
 
ETHICON, INC. (1)
4,796,603 Pad-like implant 44 1987
 
HOWMEDICA INTERNATIONAL DIV.NE PFIZER ITALIANA S.P.A. (1)
5,360,450 Prosthesis for the correction of flatfoot 64 1993
 
ORTHOPAEDIC RESEARCH INSTITUTE, INC. (1)
5,176,710 Prosthesis with low stiffness factor 55 1992
 
OSIRIS THERAPEUTICS, INC. (1)
5,197,985 Method for enhancing the implantation and differentiation of marrow-derived mesenchymal cells 162 1990
 
SHAW, ROBERT FRANCIS (1)
5,270,300 Methods and compositions for the treatment and repair of defects or lesions in cartilage or bone 141 1991
 
SOUTHERN RESEARCH INSTITUTE (1)
4,655,777 Method of producing biodegradable prosthesis and products therefrom 219 1983
 
STRYKER CORPORATION (1)
5,067,964 Articular surface repair 139 1989
 
THURGAUER KANTONALBANK, A CORPORATION CHARTERED IN AND EXISTING UNDER THE LAWS OF SWITZERLAND, THAT MAINTAINS ITS PRINCIPAL OFFICES AT: (1)
5,084,050 Implant for bone reinforcement and for anchoring bone screws, implants and implant parts 283 1989
 
UNIVERSITY OF DAYTON (1)
4,604,097 Bioabsorbable glass fibers for use in the reinforcement of bioabsorbable polymers for bone fixation devices and artificial ligaments 49 1985
 
ZIMMER, INC. (1)
4,205,400 Metallo-polymeric prosthesis with cavitied interconnection 56 1978
 
OTHER [CHECK PATENT PROFILE FOR ASSIGNMENT INFORMATION] (6)
4,502,161 Prosthetic meniscus for the repair of joints 285 1983
4,609,551 Process of and material for stimulating growth of cartilage and bony tissue at anatomical sites 141 1984
4,808,185 Tibial prosthesis, template and reamer 89 1986
4,846,835 Technique for healing lesions in cartilage 192 1987
4,904,259 Compositions and methods for repair of cartilage and bone 86 1988
5,263,987 Method and apparatus for arthroscopically replacing a bone joint 81 1991

Patent Citation Ranking

Forward Cites

Patent Info (Count) # Cites Year
 
BIOMET SPORTS MEDICINE, LLC (27)
7,608,092 Method and apparatus for performing meniscus repair 2 2004
7,608,098 Bone fixation device 25 2004
7,914,539 Tissue fixation device 4 2005
7,749,250 Soft tissue repair assembly and associated method 3 2006
8,034,090 Tissue fixation device 2 2006
7,658,751 Method for implanting soft tissue 23 2006
7,601,165 Method and apparatus for forming a self-locking adjustable suture loop 27 2006
7,857,830 Soft tissue repair and conduit device 2 2007
7,905,903 Method for tissue fixation 2 2007
7,909,851 Soft tissue repair device and associated methods 6 2008
7,905,904 Soft tissue repair device and associated methods 2 2008
8,251,998 Chondral defect repair 0 2008
8,137,382 Method and apparatus for coupling anatomical features 1 2008
8,128,658 Method and apparatus for coupling soft tissue to bone 1 2008
8,118,836 Method and apparatus for coupling soft tissue to a bone 2 2008
7,959,650 Adjustable knotless loops 3 2008
8,317,825 Soft tissue conduit device and method 0 2009
8,088,130 Method and apparatus for coupling soft tissue to a bone 1 2009
8,361,113 Method and apparatus for coupling soft tissue to a bone 0 2009
8,298,262 Method for tissue fixation 0 2009
8,303,604 Soft tissue repair device and method 0 2009
8,221,454 Apparatus for performing meniscus repair 1 2009
8,409,253 Soft tissue repair assembly and associated method 0 2010
8,273,106 Soft tissue repair and conduit device 0 2010
8,337,525 Soft tissue repair device and associated methods 0 2011
8,292,921 Soft tissue repair device and associated methods 0 2011
8,231,654 Adjustable knotless loops 1 2011
 
CONFORMIS, INC. (19)
7,468,075 Methods and compositions for articular repair 58 2002
7,799,077 Minimally invasive joint implant with 3-dimensional geometry matching the articular surfaces 30 2003
7,796,791 Methods for determining meniscal size and shape and for devising treatment 21 2003
7,618,451 Patient selectable joint arthroplasty devices and surgical tools facilitating increased accuracy, speed and simplicity in performing total and partial joint arthroplasty 56 2003
7,534,263 Surgical tools facilitating increased accuracy, speed and simplicity in performing joint arthroplasty 51 2004
7,717,956 Joint arthroplasty devices formed in situ 18 2005
8,066,708 Patient selectable joint arthroplasty devices and surgical tools 7 2007
8,083,745 Surgical tools for arthroplasty 11 2008
8,105,330 Patient selectable joint arthroplasty devices and surgical tools 5 2008
8,062,302 Surgical tools for arthroplasty 7 2008
7,981,158 Patient selectable joint arthroplasty devices and surgical tools 32 2008
8,343,218 Methods and compositions for articular repair 0 2008
8,337,507 Methods and compositions for articular repair 0 2008
8,122,582 Surgical tools facilitating increased accuracy, speed and simplicity in performing joint arthroplasty 5 2009
8,377,129 Joint arthroplasty devices and surgical tools 0 2009
8,234,097 Automated systems for manufacturing patient-specific orthopedic implants and instrumentation 0 2010
8,366,771 Surgical tools facilitating increased accuracy, speed and simplicity in performing joint arthroplasty 0 2010
8,337,501 Patient selectable joint arthroplasty devices and surgical tools 0 2010
8,077,950 Methods for determining meniscal size and shape and for devising treatment 6 2010
 
BONUTTI SKELETAL INNOVATIONS LLC (17)
6,702,821 Instrumentation for minimally invasive joint replacement and methods for using same 116 2001
6,770,078 Movable knee implant and methods therefor 74 2001
7,104,996 Method of performing surgery 64 2002
7,635,390 Joint replacement component having a modular articulating surface 8 2003
8,133,229 Knee arthroplasty method 1 2003
7,806,896 Knee arthroplasty method 29 2003
7,959,635 Limited incision total joint replacement methods 0 2004
7,892,236 System and method for total joint replacement 1 2005
7,510,557 Cutting guide 20 2005
7,806,897 Knee arthroplasty and preservation of the quadriceps mechanism 6 2005
7,749,229 Total knee arthroplasty through shortened incision 8 2005
7,708,740 Method for total knee arthroplasty and resecting bone in situ 5 2005
7,708,741 Method of preparing bones for knee replacement surgery 13 2005
7,931,690 Method of resurfacing an articular surface of a bone 5 2007
7,828,852 Inlaid articular implant 1 2007
7,837,736 Minimally invasive surgical systems and methods 5 2007
8,425,522 Joint replacement method 0 2010
 
DEPUY PRODUCTS, INC. (17)
8,337,537 Device from naturally occurring biologically derived materials 0 2002
8,092,529 Meniscus regeneration device 0 2002
8,025,896 Porous extracellular matrix scaffold and method 1 2002
8,012,205 Cartilage repair and regeneration device 0 2002
7,914,808 Hybrid biologic/synthetic porous extracellular matrix scaffolds 1 2002
7,361,195 Cartilage repair apparatus and method 20 2002
7,201,917 Porous delivery scaffold and method 22 2002
7,163,563 Unitary surgical device and method 37 2002
7,666,230 Implant device for cartilage regeneration in load bearing articulation regions 9 2003
7,819,918 Implantable tissue repair device 3 2003
7,513,866 Intestine processing device and associated method 0 2004
7,354,627 Method for organizing the assembly of collagen fibers and compositions formed therefrom 6 2004
7,569,233 Hybrid biologic-synthetic bioabsorbable scaffolds 2 2005
7,595,062 Joint resurfacing orthopaedic implant and associated method 1 2005
8,216,319 Method of repairing a knee joint 0 2005
7,871,440 Unitary surgical device and method 1 2006
8,128,703 Fixed-bearing knee prosthesis having interchangeable components 0 2009
 
ARTHROSURFACE, INC. (14)
7,678,151 System and method for joint resurface repair 13 2003
7,510,558 System and method for joint resurface repair 19 2003
7,618,462 System and method for joint resurface repair 12 2004
7,896,885 Retrograde delivery of resurfacing devices 5 2004
8,361,159 System for articular surface replacement 0 2005
7,914,545 System and method for retrograde procedure 6 2006
7,828,853 Articular surface implant and delivery system 7 2006
7,713,305 Articular surface implant 5 2006
7,951,163 Retrograde excision system and apparatus 5 2006
8,177,841 System and method for joint resurface repair 2 2008
7,896,883 Bone resurfacing system and method 4 2009
7,857,817 System and method for joint resurface repair 4 2009
8,147,559 System and method for joint resurface repair 2 2009
8,388,624 Trochlear resurfacing system and method 0 2010
 
DEPUY MITEK, INC. (12)
7,824,701 Biocompatible scaffold for ligament or tendon repair 13 2003
8,226,715 Scaffold for connective tissue repair 0 2003
7,316,822 Conformable tissue repair implant capable of injection delivery 24 2003
8,137,686 Nonwoven tissue scaffold 3 2004
8,110,210 Nonwoven tissue scaffold 0 2004
8,016,867 Graft fixation device and method 0 2004
8,221,780 Nonwoven tissue scaffold 0 2006
8,105,621 Nonwoven tissue scaffold 0 2006
7,875,296 Conformable tissue repair implant capable of injection delivery 14 2007
8,308,814 Methods and devices for preparing and implanting tissue scaffolds 0 2009
8,241,298 Methods and devices for delivering and affixing tissue scaffolds 0 2009
8,137,702 Conformable tissue repair implant capable of injection delivery 1 2010
 
ETHICON, INC. (11)
6,371,958 Scaffold fixation device for use in articular cartilage repair 77 2000
6,423,252 Methods of making micropatterned foams 11 2000
6,852,330 Reinforced foam implants with enhanced integrity for soft tissue repair and regeneration 43 2000
6,599,323 Reinforced tissue implants and methods of manufacture and use 72 2000
6,743,232 Tissue scaffold anchor for cartilage repair 37 2001
6,575,986 Scaffold fixation device for use in articular cartilage repair 33 2001
6,626,950 Composite scaffold with post anchor for the repair and regeneration of tissue 75 2001
7,192,604 Implantable biodegradable devices for musculoskeletal repair or regeneration 12 2001
6,989,034 Attachment of absorbable tissue scaffolds to fixation devices 59 2002
6,884,428 Use of reinforced foam implants with enhanced integrity for soft tissue repair and regeneration 56 2002
7,901,461 Viable tissue repair implants and methods of use 13 2003
 
PUGET BIOVENTURES LLC (11)
7,967,822 Methods and apparatus for orthopedic implants 0 2004
7,815,645 Methods and apparatus for pinplasty bone resection 5 2005
8,287,545 Methods and apparatus for enhanced retention of prosthetic implants 0 2005
8,114,083 Methods and apparatus for improved drilling and milling tools for resection 0 2005
8,021,368 Methods and apparatus for improved cutting tools for resection 0 2005
7,857,814 Methods and apparatus for minimally invasive arthroplasty 0 2005
8,353,914 Methods and apparatus for improved profile based resection 0 2007
8,062,377 Methods and apparatus for knee arthroplasty 0 2007
8,298,238 Methods and apparatus for pivotable guide surfaces for arthroplasty 0 2008
8,088,167 Femoral prosthetic implant 0 2009
7,935,151 Femoral prosthetic implant 1 2010
 
BIOMET MANUFACTURING CORP. (10)
7,837,690 Method and apparatus for less invasive knee resection 2 2003
7,488,324 Femoral guide for implanting a femoral knee prosthesis 25 2003
7,887,542 Method and apparatus for less invasive knee resection 0 2004
7,789,885 Instrumentation for knee resection 0 2005
7,695,479 Femoral sizer 1 2005
7,780,672 Femoral adjustment device and associated method 10 2006
7,695,520 Prosthesis and implementation system 0 2006
8,070,752 Patient specific alignment guide and inter-operative adjustment 4 2008
8,123,758 Femoral guide for implanting a femoral knee prosthesis 0 2009
8,343,227 Knee prosthesis assembly with ligament link 0 2010
 
MUSCULOSKELETAL TRANSPLANT FOUNDATION (9)
7,901,457 Cartilage allograft plug 6 2003
7,488,348 Cartilage allograft plug 8 2005
7,815,926 Implant for articular cartilage repair 2 2006
7,837,740 Two piece cancellous construct for cartilage repair 4 2007
RE42208 Glue for cartilage repair 3 2008
8,221,500 Cartilage allograft plug 0 2008
8,435,551 Cancellous construct with support ring for repair of osteochondral defects 0 2009
RE43258 Glue for cartilage repair 0 2010
8,292,968 Cancellous constructs, cartilage particles and combinations of cancellous constructs and cartilage particles 0 2011
 
THE CLEVELAND CLINIC FOUNDATION (9)
6,982,298 Hydroxyphenyl cross-linked macromolecular network and applications thereof 9 2004
7,465,766 Hydroxyphenyl cross-linked macromolecular network and applications thereof 2 2005
7,368,502 Hydroxyphenyl cross-linked macromolecular network and applications thereof 2 2005
8,207,262 Hydroxyphenyl cross-linked macromolecular network and applications thereof 0 2008
8,138,265 Hydroxyphenyl cross-linked macromolecular network and applications thereof 2 2009
8,021,350 Hydroxyphenyl cross-linked macromolecular network and applications thereof 0 2009
8,080,260 Molecular enhancement of extracellular matrix and methods of use 0 2009
8,137,688 Hydroxyphenyl cross-linked macromolecular network and applications thereof 1 2009
8,410,180 Methods to treat urinary incontinence 0 2009
 
ETHICON ENDO-SURGERY, INC. (8)
6,355,699 Process for manufacturing biomedical foams 59 1999
6,333,029 Porous tissue scaffoldings for the repair of regeneration of tissue 106 1999
6,306,424 Foam composite for the repair or regeneration of tissue 121 1999
6,534,084 Porous tissue scaffoldings for the repair or regeneration of tissue 66 2000
6,365,149 Porous tissue scaffoldings for the repair or regeneration of tissue 63 2000
7,112,417 Foam composite for the repair or regeneration of tissue 15 2001
6,712,850 Porous tissue scaffolds for the repair and regeneration of dermal tissue 2 2001
8,187,326 Attachment of absorbable tissue scaffolds to fixation devices 0 2002
 
VERIGEN AG (8)
6,866,668 Methods, instruments and materials for chondrocyte cell transplantation 17 2001
6,569,172 Method, instruments, and kit for autologous transplantation 31 2001
6,592,598 Method, instruments, and kit for autologous transplantation 13 2002
6,599,300 Method, instruments, and kit for autologous transplantation 10 2002
6,592,599 Method, instruments, and kit for autologous transplantation 12 2002
6,599,301 Method, instruments, and kit for autologous transplantation 16 2002
7,137,989 Method, instruments, and kit for autologous transplantation 10 2003
7,048,750 Method, instruments, and kits for autologous transplantation 9 2003
 
THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (7)
8,265,730 Assessing the condition of a joint and preventing damage 0 2001
8,036,729 Assessing the condition of a joint and devising treatment 12 2004
7,881,768 Assessing the condition of a joint and devising treatment 28 2007
8,112,142 Assessing the condition of a joint and devising treatment 9 2007
RE43282 Assessing the condition of a joint and devising treatment 8 2008
8,369,926 Assessing the condition of a joint and devising treatment 0 2011
8,306,601 Assessing the condition of a joint and devising treatment 0 2011
 
ACTIVE IMPLANTS CORPORATION (5)
8,192,491 Meniscus prosthetic device 0 2007
8,361,147 Meniscus prosthetic devices with anti-migration features 0 2008
8,016,884 Tensioned meniscus prosthetic devices and associated methods 4 2008
7,991,599 Meniscus prosthetic device selection and implantation methods 3 2008
7,611,653 Manufacturing and material processing for prosthetic devices 11 2008
 
DEPUY ORTHOPAEDICS, INC. (5)
6,251,143 Cartilage repair unit 131 1999
6,468,314 Cartilage repair unit 49 2001
7,172,606 Soft tissue repair material fixation apparatus and method 1 2003
7,160,333 Reinforced small intestinal submucosa 25 2003
7,799,089 Reinforced small intestinal submucosa 1 2006
 
ABS CORPORATION (3)
6,632,246 Cartilage repair plug 39 2000
6,626,945 Cartilage repair plug 66 2001
6,852,125 Cartilage repair plug 26 2003
 
MEDICINELODGE, INC. (3)
7,488,347 Transosseous graft retention system and method 2 2005
7,641,694 Line lock graft retention system and method 0 2005
7,722,644 Compact line locks and methods 2 2005
 
BIOMERIX CORPORATION (2)
7,763,077 Repair of spinal annular defects and annulo-nucleoplasty regeneration 17 2003
7,803,395 Reticulated elastomeric matrices, their manufacture and use in implantable devices 2 2004
 
COVIDIEN LP (2)
6,712,822 Apparatus and method for the repair of articular cartilage defects 12 2002
8,157,805 Apparatus and method for the repair of articular cartilage defects 0 2004
 
DEPUY SPINE, INC. (2)
6,645,945 Method of treating diseased, injured or abnormal cartilage with hyaluronic acid and growth factors 4 1999
7,902,172 Method of promoting bone growth with hyaluronic acid and growth factors 0 2004
 
ORTHOGENE LLC (2)
6,630,457 Functionalized derivatives of hyaluronic acid, formation of hydrogels in situ using same, and methods for making and using same 19 1998
7,196,180 Functionalized derivatives of hyaluronic acid, formation of hydrogels in situ using same, and methods for making and using same 10 2003
 
ORTHORIFLING SYSTEMS, LLC (2)
6,312,470 Acetabulum spacing device 4 2000
6,641,615 Acetabulum spacing device 0 2001
 
RTI BIOLOGICS, INC. (2)
6,893,462 Soft and calcified tissue implants 47 2001
7,513,910 Soft and calcified tissue implants 21 2004
 
THE RESEARCH FOUNDATION OF STATE UNIVERSITY OF NEW YORK (2)
6,312,952 In vitro cell culture device including cartilage and methods of using the same 3 2000
6,465,205 In vitro cell culture device including cartilage and methods of using the same 14 2001
 
ARTHRO ALLIANCE LLC (1)
6,132,468 Arthroscopic replacement of cartilage using flexible inflatable envelopes 125 1998
 
CORPORATION DE L'ECOLE POLYTECHNIQUE DE MONTREAL (1)
8,007,823 Microporous articles comprising biodegradable medical polymers, method of preparation thereof and method of use thereof 0 2004
 
DEPUY SYNTHES PRODUCTS, LLC (1)
8,366,787 Hybrid biologic-synthetic bioabsorbable scaffolds 0 2002
 
FIDIA ADVANCED BIOPOLYMERS S.R.L. (1)
7,722,616 Use of a biological material containing three-dimensional scaffolds of hyaluronic acid derivatives for the preparation of implants in arthroscopy and kit for instruments for implanting said biological material by arthroscopy 0 2001
 
GENZYME CORPORATION (1)
8,323,675 Soft tissue prosthesis for repairing a defect of an abdominal wall or a pelvic cavity wall 0 2005
 
HOWMEDICA OSTEONICS CORP. (1)
8,268,100 Laser-produced porous surface 0 2010
 
IMDS CORPORATION (1)
8,388,655 Compact line locks and methods 0 2010
 
LAWLER, JOHN (1)
6,849,594 Purification and use of human recombinant cartilage oligomeric matrix protein 3 2000
 
MARTEC LLC (1)
7,615,054 Bicompartmental knee implant and method 11 2003
 
MASSACHUSETTS INSTITUTE OF TECHNOLOGY (1)
7,815,826 Manufacturing process, such as three-dimensional printing, including solvent vapor filming and the like 0 2005
 
MEDLDEN, LLC (1)
7,585,323 In vitro mechanical loading of musculoskeletal tissues 1 2001
 
MEDTRONIC PS MEDICAL, INC. (1)
6,572,623 Method and apparatus for attaching a cranial flap 4 2000
 
POREX SURGICAL (1)
8,142,886 Porous laser sintered articles 0 2008
 
PUGET BIO VENTURES LLC (1)
8,430,932 Femoral prosthetic implant 0 2011
 
TRUSTEES OF TUFTS COLLEGE (1)
6,287,340 Bioengineered anterior cruciate ligament 31 1999
 
VELOCITY FINANCIAL GROUP INC., ITS SUCCESSORS AND ASSIGNS (1)
8,192,759 Matrix made of polyester polymers entangled with hyaluronic polymers useful for supporting tissue repair 0 2005
 
WARSAW ORTHOPEDIC, INC. (1)
8,057,458 Method for treating facet pain 0 2006
 
ZIMMER ORTHOBIOLOGICS, INC. (1)
RE43714 Preparation for repairing cartilage defects or cartilage/bone defects in human or animal joints 1 2000
 
OTHER [CHECK PATENT PROFILE FOR ASSIGNMENT INFORMATION] (5)
6,171,340 Method and device for regenerating cartilage in articulating joints 120 1999
6,530,956 Resorbable scaffolds to promote cartilage regeneration 68 1999
6,376,742 In vivo tissue engineering with biodegradable polymers 24 2000
8,444,968 Cartilage repair methods 0 2006
8,439,926 Patient selectable joint arthroplasty devices and surgical tools 0 2009