US Patent No: 5,769,899

Number of patents in Portfolio can not be more than 2000

Cartilage repair unit

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ATTORNEY / AGENT: (SPONSORED)

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Abstract

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A bio-absorbable cartilage repair system for regenerating damaged or destroyed articular cartilage on the surface of a bone by establishing a chondrogenic growth-supporting matrix between an area of removed damaged or destroyed articular cartilage and the adjacent healthy cancellous bone. The system is at least one assembly of a bio-absorbable delivery unit, configured and dimensioned to be mounted in both the removed area and the adjacent healthy area, and a porous bio-absorbable insert supported by and in the delivery unit and establishing communication between the removed area and the adjacent healthy area for a chondrogenic growth-supporting matrix. The insert preferably includes a repair factor (e.g., a growth factor, an attachment factor, or both) releasably disposed in the insert to assist in establishing the chondrogenic growth-supporting matrix.

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First Claim

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Patent Owner(s)

Patent OwnerAddressTotal Patents
DEPUY ORTHOPAEDICS, INC.WARSAW, IN254
NORTH SHORE UNIVERSITY HOSPITAL RESEARCH CORPORATIONMANHASSET, NY6

International Classification(s)

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Grande, Jr Daniel Anthony Seacliff, NY 1 405
Schwartz, Robert Elliott Old Westbury, NY 1 405

Cited Art Landscape

Patent Info (Count) # Cites Year
 
Other [Check patent profile for assignment information] (6)
* 4,502,161 Prosthetic meniscus for the repair of joints 472 1983
* 4,609,551 Process of and material for stimulating growth of cartilage and bony tissue at anatomical sites 238 1984
* 4,808,185 Tibial prosthesis, template and reamer 120 1986
* 4,846,835 Technique for healing lesions in cartilage 305 1987
* 4,904,259 Compositions and methods for repair of cartilage and bone 111 1988
* 5,263,987 Method and apparatus for arthroscopically replacing a bone joint 124 1991
 
STRYKER CORPORATION (1)
* 5,067,964 Articular surface repair 242 1989
 
DEPUY ORTHOPAEDICS, INC. (1)
* 5,123,927 Method and apparatus for antibiotic knee prothesis 135 1991
 
Howmedica International Div.ne Pfizer Italiana S.p.A. (1)
* 5,360,450 Prosthesis for the correction of flatfoot 101 1993
 
SOUTHERN RESEARCH INSTITUTE (1)
* 4,655,777 Method of producing biodegradable prosthesis and products therefrom 286 1983
 
THURGAUER KANTONALBANK, A CORPORATION CHARTERED IN AND EXISTING UNDER THE LAWS OF SWITZERLAND, THAT MAINTAINS ITS PRINCIPAL OFFICES AT: (1)
* 5,084,050 Implant for bone reinforcement and for anchoring bone screws, implants and implant parts 398 1989
 
ADVANCED BIOHEALING, INC. (1)
* 4,963,489 Three-dimensional cell and tissue culture system 250 1988
 
ORTHOPAEDIC RESEARCH INSTITUTE, INC., A CORP. OF KS (1)
* 5,176,710 Prosthesis with low stiffness factor 76 1992
 
University of Dayton (1)
* 4,604,097 Bioabsorbable glass fibers for use in the reinforcement of bioabsorbable polymers for bone fixation devices and artificial ligaments 60 1985
 
MESOBLAST INTERNATIONAL SÀRL (1)
* 5,197,985 Method for enhancing the implantation and differentiation of marrow-derived mesenchymal cells 310 1990
 
BAXTER INTERNATIONAL INC. (1)
* 4,627,853 Method of producing prostheses for replacement of articular cartilage and prostheses so produced 330 1985
 
SHAW, ROBERT FRANCIS (1)
* 5,270,300 Methods and compositions for the treatment and repair of defects or lesions in cartilage or bone 267 1991
 
ETHICON, INC. (1)
* 4,796,603 Pad-like implant 51 1987
 
BIOCON OY (1)
* 5,084,051 Layered surgical biocomposite material 248 1988
 
LIFESHIELD SCIENCES LLC (1)
* 2004/0158,312 Braided endoluminal device having tapered filaments 20 2003
 
ReGen Corporation (2)
* 4,880,429 Prosthetic meniscus 273 1987
* 5,306,311 Prosthetic articular cartilage 408 1991
* Cited By Examiner

Patent Citation Ranking

Forward Cite Landscape

Patent Info (Count) # Cites Year
 
Other [Check patent profile for assignment information] (7)
6,171,340 Method and device for regenerating cartilage in articulating joints 233 1999
* 6,530,956 Resorbable scaffolds to promote cartilage regeneration 120 1999
6,376,742 In vivo tissue engineering with biodegradable polymers 48 2000
* 2003/0193,104 Reinforced tissue implants and methods of manufacture and use 31 2003
* 2004/0146,544 Porous tissue scaffolds for the repair and regeneration of dermal tissue 3 2004
* 2005/0265,959 Hydroxyphenyl cross-linked macromolecular network and applications thereof 0 2005
* 2008/0167,716 CARTILAGE REPAIR APPARATUS AND METHOD 11 2008
 
CONFORMIS, INC. (90)
7,468,075 Methods and compositions for articular repair 244 2002
* 2003/0216,669 Methods and compositions for articular repair 185 2002
7,799,077 Minimally invasive joint implant with 3-dimensional geometry matching the articular surfaces 93 2003
* 2004/0133,276 Minimally invasive joint implant with 3-Dimensional geometry matching the articular surfaces 234 2003
8,932,363 Methods for determining meniscal size and shape and for devising treatment 3 2003
7,796,791 Methods for determining meniscal size and shape and for devising treatment 78 2003
7,618,451 Patient selectable joint arthroplasty devices and surgical tools facilitating increased accuracy, speed and simplicity in performing total and partial joint arthroplasty 232 2003
* 2004/0236,424 Patient selectable joint arthroplasty devices and surgical tools facilitating increased accuracy, speed and simplicity in performing total and partial joint arthroplasty 292 2003
8,545,569 Patient selectable knee arthroplasty devices 43 2004
8,882,847 Patient selectable knee joint arthroplasty devices 14 2004
7,534,263 Surgical tools facilitating increased accuracy, speed and simplicity in performing joint arthroplasty 202 2004
* 2005/0234,461 Surgical tools facilitating increased accuracy, speed and simplicity in performing joint arthroplasty 212 2004
7,717,956 Joint arthroplasty devices formed in situ 52 2005
* 2007/0250,169 Joint arthroplasty devices formed in situ 139 2005
8,066,708 Patient selectable joint arthroplasty devices and surgical tools 110 2007
* 2007/0198,022 Patient Selectable Joint Arthroplasty Devices and Surgical Tools 263 2007
8,617,242 Implant device and method for manufacture 40 2008
8,083,745 Surgical tools for arthroplasty 127 2008
8,105,330 Patient selectable joint arthroplasty devices and surgical tools 102 2008
8,062,302 Surgical tools for arthroplasty 86 2008
7,981,158 Patient selectable joint arthroplasty devices and surgical tools 175 2008
* 2008/0281,426 Patient Selectable Joint Arthroplasty Devices and Surgical Tools 204 2008
8,951,260 Surgical cutting guide 9 2008
8,343,218 Methods and compositions for articular repair 71 2008
8,337,507 Methods and compositions for articular repair 71 2008
8,122,582 Surgical tools facilitating increased accuracy, speed and simplicity in performing joint arthroplasty 74 2009
8,682,052 Implants for altering wear patterns of articular surfaces 32 2009
8,439,926 Patient selectable joint arthroplasty devices and surgical tools 56 2009
9,308,091 Devices and methods for treatment of facet and other joints 0 2009
8,460,304 Joint arthroplasty devices and surgical tools 54 2009
8,377,129 Joint arthroplasty devices and surgical tools 75 2009
8,234,097 Automated systems for manufacturing patient-specific orthopedic implants and instrumentation 85 2010
8,480,754 Patient-adapted and improved articular implants, designs and related guide tools 54 2010
8,500,740 Patient-specific joint arthroplasty devices for ligament repair 72 2010
8,709,089 Minimally invasive joint implant with 3-dimensional geometry matching the articular surfaces 36 2010
8,551,099 Surgical tools for arthroplasty 45 2010
8,366,771 Surgical tools facilitating increased accuracy, speed and simplicity in performing joint arthroplasty 68 2010
8,337,501 Patient selectable joint arthroplasty devices and surgical tools 89 2010
9,055,953 Methods and compositions for articular repair 10 2010
9,023,050 Surgical tools for arthroplasty 0 2010
8,768,028 Methods and compositions for articular repair 27 2010
8,690,945 Patient selectable knee arthroplasty devices 33 2010
8,585,708 Patient selectable joint arthroplasty devices and surgical tools 1 2010
8,945,230 Patient selectable knee joint arthroplasty devices 3 2010
8,771,365 Patient-adapted and improved orthopedic implants, designs, and related tools 26 2010
8,077,950 Methods for determining meniscal size and shape and for devising treatment 59 2010
9,220,516 Patient selectable joint arthroplasty devices and surgical tools 0 2011
9,220,517 Patient selectable joint arthroplasty devices and surgical tools 0 2011
8,556,983 Patient-adapted and improved orthopedic implants, designs and related tools 44 2011
8,735,773 Implant device and method for manufacture 43 2011
9,295,482 Patient selectable joint arthroplasty devices and surgical tools 0 2011
8,623,026 Patient selectable joint arthroplasty devices and surgical tools incorporating anatomical relief 36 2011
8,974,539 Patient-adapted and improved articular implants, designs and related guide tools 2 2011
8,926,706 Patient-adapted and improved articular implants, designs and related guide tools 3 2011
8,906,107 Patient-adapted and improved orthopedic implants, designs and related tools 4 2011
8,657,827 Surgical tools for arthroplasty 38 2011
9,107,679 Patient selectable joint arthroplasty devices and surgical tools 6 2011
9,084,617 Patient selectable joint arthroplasty devices and surgical tools 6 2011
8,634,617 Methods for determining meniscal size and shape and for devising treatment 40 2011
9,186,161 Surgical tools for arthroplasty 0 2011
9,020,788 Patient-adapted and improved articular implants, designs and related guide tools 0 2012
9,216,025 Joint arthroplasty devices and surgical tools 0 2012
9,066,728 Surgical tools facilitating increased accuracy, speed and simplicity in performing joint arthroplasty 8 2012
8,641,716 Joint arthroplasty devices and surgical tools 39 2012
8,617,172 Joint arthroplasty devices and surgical tools 40 2012
8,568,479 Joint arthroplasty devices and surgical tools 41 2012
8,568,480 Joint arthroplasty devices and surgical tools 41 2012
8,562,611 Joint arthroplasty devices and surgical tools 43 2012
8,562,618 Joint arthroplasty devices and surgical tools 43 2012
8,561,278 Joint arthroplasty devices and surgical tools 43 2012
8,556,906 Joint arthroplasty devices and surgical tools 43 2012
8,556,907 Joint arthroplasty devices and surgical tools 43 2012
8,551,102 Joint arthroplasty devices and surgical tools 43 2012
8,551,103 Joint arthroplasty devices and surgical tools 46 2012
8,551,169 Joint arthroplasty devices and surgical tools 44 2012
8,529,630 Patient selectable joint arthroplasty devices and surgical tools 43 2012
9,107,680 Patient selectable joint arthroplasty devices and surgical tools 6 2012
8,998,915 Joint arthroplasty devices and surgical tools 8 2013
9,320,620 Patient-adapted and improved articular implants, designs and related guide tools 0 2013
9,308,053 Patient-specific joint arthroplasty devices for ligament repair 0 2013
9,333,085 Patient selectable knee arthroplasty devices 0 2013
9,125,672 Joint arthroplasty devices and surgical tools 4 2013
9,125,673 Joint arthroplasty devices and surgical tools 4 2013
9,072,531 Patient selectable joint arthroplasty devices and surgical tools 8 2013
8,951,259 Patient selectable joint arthroplasty devices and surgical tools 12 2013
8,849,621 Patient selectable joint arthroplasty devices and surgical tools 0 2013
9,326,780 Patient selectable joint arthroplasty devices and surgical tools incorporating anatomical relief 0 2014
8,965,088 Methods for determining meniscal size and shape and for devising treatment 3 2014
9,180,015 Implants for altering wear patterns of articular surfaces 0 2014
9,186,254 Patient selectable knee arthroplasty devices 0 2014
 
Active Implants LLC (2)
9,326,863 Meniscus prosthetic device selection and implantation methods 0 2011
9,320,606 Meniscus prosthetic device 0 2012
 
BIOSHAPE SOLUTIONS INC (2)
* 2010/0130,959 DEVICE AND METHOD FOR DELIVERY OF THERAPEUTIC AGENTS VIA ARTIFICIAL INTERNAL IMPLANTS 0 2009
* 2011/0178,465 DEVICE AND METHOD FOR DELIVERY OF THERAPEUTIC AGENTS VIA INTERNAL IMPLANTS 0 2010
 
ZIMMER, INC. (9)
8,480,757 Implants and methods for repair, replacement and treatment of disease 9 2006
8,765,165 Particulate cartilage system 1 2010
8,834,914 Treatment methods using a particulate cadaveric allogenic juvenile cartilage particles 1 2010
8,784,863 Particulate cadaveric allogenic cartilage system 1 2010
8,652,507 Juvenile cartilage composition 7 2010
9,138,318 Apparatus for forming an implant 0 2011
8,524,268 Cadaveric allogenic human juvenile cartilage implant 4 2011
8,518,433 Method of treating an osteochondral defect 5 2011
8,753,406 Osteochondral graft delivery device and uses thereof 2 2013
 
DEPUY MITEK, LLC (27)
6,852,330 Reinforced foam implants with enhanced integrity for soft tissue repair and regeneration 109 2000
6,884,428 Use of reinforced foam implants with enhanced integrity for soft tissue repair and regeneration 121 2002
* 2003/0147,935 Use of reinforced foam implants with enhanced integrity for soft tissue repair and regeneration 20 2002
7,824,701 Biocompatible scaffold for ligament or tendon repair 36 2003
* 2004/0078,077 Biocompatible scaffold for ligament or tendon repair 82 2003
* 2004/0078,090 Biocompatible scaffolds with tissue fragments 140 2003
8,226,715 Scaffold for connective tissue repair 72 2003
7,316,822 Conformable tissue repair implant capable of injection delivery 67 2003
* 2005/0113,937 Conformable tissue repair implant capable of injection delivery 30 2003
* 2005/0177,249 Scaffolds with viable tissue 57 2004
8,657,881 Meniscal repair scaffold 0 2004
8,137,686 Nonwoven tissue scaffold 15 2004
2005/0232,967 Nonwoven tissue scaffold 21 2004
* 2005/0234,549 Meniscal repair scaffold 53 2004
8,691,259 Reinforced foam implants with enhanced integrity for soft tissue repair and regeneration 0 2005
8,221,780 Nonwoven tissue scaffold 8 2006
* 2007/0031,470 NONWOVEN TISSUE SCAFFOLD 18 2006
8,449,561 Graft fixation device combination 0 2007
8,308,814 Methods and devices for preparing and implanting tissue scaffolds 0 2009
8,241,298 Methods and devices for delivering and affixing tissue scaffolds 4 2009
8,637,066 Biocompatible scaffold for ligament or tendon repair 1 2010
8,641,775 Viable tissue repair implants and methods of use 5 2011
8,496,970 Conformable tissue repair implant capable of injection delivery 5 2012
8,895,045 Method of preparation of bioabsorbable porous reinforced tissue implants and implants thereof 0 2012
9,211,362 Scaffold for connective tissue repair 0 2012
9,149,369 Methods and devices for delivering and affixing tissue scaffolds 0 2012
8,469,980 Methods and devices for preparing and implanting tissue scaffolds 2 2012
 
CORPORATION DE L'ÉCOLE POLYTECHNIQUE DE MONTRÉAL (2)
8,007,823 Microporous articles comprising biodegradable medical polymers, method of preparation thereof and method of use thereof 1 2004
* 2007/0116,737 Microporous articles comprising biodegradable medical polymers, method of preparation thereof and method of use thereof 3 2004
 
PFIZER INC. (1)
* 2003/0191,107 3-(Imidazolyl)-2-aminopropanoic acids 2 2003
 
ORTHORIFLING SYSTEMS, LLC (2)
6,312,470 Acetabulum spacing device 5 2000
6,641,615 Acetabulum spacing device 0 2001
 
ETHICON ENDO-SURGERY, INC. (10)
* 6,355,699 Process for manufacturing biomedical foams 140 1999
6,333,029 Porous tissue scaffoldings for the repair of regeneration of tissue 259 1999
6,306,424 Foam composite for the repair or regeneration of tissue 209 1999
6,534,084 Porous tissue scaffoldings for the repair or regeneration of tissue 151 2000
6,365,149 Porous tissue scaffoldings for the repair or regeneration of tissue 113 2000
* 7,112,417 Foam composite for the repair or regeneration of tissue 31 2001
* 2003/0077,311 Foam composite for the repair or regeneration of tissue 58 2001
6,712,850 Porous tissue scaffolds for the repair and regeneration of dermal tissue 7 2001
* 8,187,326 Attachment of absorbable tissue scaffolds to fixation devices 6 2002
* 2003/0220,700 Attachment of absorbable tissue scaffolds ot fixation devices 24 2002
 
Puget Bio Ventures LLC (2)
8,603,095 Apparatuses for femoral and tibial resection 0 2011
8,430,932 Femoral prosthetic implant 0 2011
 
ETHICON, INC. (10)
6,371,958 Scaffold fixation device for use in articular cartilage repair 163 2000
* 6,423,252 Methods of making micropatterned foams 26 2000
6,599,323 Reinforced tissue implants and methods of manufacture and use 193 2000
6,743,232 Tissue scaffold anchor for cartilage repair 73 2001
6,575,986 Scaffold fixation device for use in articular cartilage repair 50 2001
6,626,950 Composite scaffold with post anchor for the repair and regeneration of tissue 170 2001
7,192,604 Implantable biodegradable devices for musculoskeletal repair or regeneration 25 2001
* 2002/0131,989 Implantable biodegradable devices for musculoskeletal repair or regeneration 8 2001
6,989,034 Attachment of absorbable tissue scaffolds to fixation devices 104 2002
7,901,461 Viable tissue repair implants and methods of use 40 2003
 
PUGET BIOVENTURES LLC (14)
7,967,822 Methods and apparatus for orthopedic implants 4 2004
7,815,645 Methods and apparatus for pinplasty bone resection 35 2005
8,287,545 Methods and apparatus for enhanced retention of prosthetic implants 7 2005
8,114,083 Methods and apparatus for improved drilling and milling tools for resection 1 2005
8,021,368 Methods and apparatus for improved cutting tools for resection 20 2005
7,857,814 Methods and apparatus for minimally invasive arthroplasty 7 2005
8,353,914 Methods and apparatus for improved profile based resection 0 2007
8,062,377 Methods and apparatus for knee arthroplasty 8 2007
8,740,906 Method and apparatus for wireplasty bone resection 0 2008
8,298,238 Methods and apparatus for pivotable guide surfaces for arthroplasty 1 2008
8,088,167 Femoral prosthetic implant 9 2009
7,935,151 Femoral prosthetic implant 18 2010
9,066,804 Method and apparatus for femoral and tibial resection 1 2011
9,192,391 Method for minimally invasive total knee arthroplasty 0 2015
 
WARSAW ORTHOPEDIC, INC. (5)
* 2007/0227,547 Treatment of the vertebral column 21 2006
* 2007/0213,718 Treatment of the vertebral column 33 2006
* 2007/0213,822 Treatment of the vertebral column 53 2006
* 2008/0051,796 Graft retention tack 0 2006
8,057,458 Method for treating facet pain 0 2006
 
ARTHRO ALLIANCE LLC (1)
* 6,132,468 Arthroscopic replacement of cartilage using flexible inflatable envelopes 212 1998
 
KABUSHIKI KAISHA KOBE SEIKO SHO (KOBE STEEL, LTD.) (1)
* 2011/0139,761 FLUX-CORED WIRE FOR STAINLESS STEEL ARC WELDING 1 2010
 
Medlden, LLC (1)
7,585,323 In vitro mechanical loading of musculoskeletal tissues 2 2001
 
GENZYME CORPORATION (2)
8,323,675 Soft tissue prosthesis for repairing a defect of an abdominal wall or a pelvic cavity wall 7 2005
8,460,695 Making a soft tissue prosthesis for repairing a defect of an abdominal wall or a pelvic cavity wall 0 2012
 
THE CLEVELAND CLINIC FOUNDATION (14)
6,982,298 Hydroxyphenyl cross-linked macromolecular network and applications thereof 18 2004
* 2004/0147,673 Hydroxyphenyl cross-linked macromolecular network and applications thereof 1 2004
7,465,766 Hydroxyphenyl cross-linked macromolecular network and applications thereof 6 2005
7,368,502 Hydroxyphenyl cross-linked macromolecular network and applications thereof 4 2005
8,207,262 Hydroxyphenyl cross-linked macromolecular network and applications thereof 2 2008
* 2009/0042,294 Hydroxyphenyl cross-linked macromolecular network and applications thereof 2 2008
8,138,265 Hydroxyphenyl cross-linked macromolecular network and applications thereof 4 2009
8,021,350 Hydroxyphenyl cross-linked macromolecular network and applications thereof 2 2009
* 2009/0143,766 Hydroxyphenyl cross-linked macromolecular network and applications thereof 3 2009
8,080,260 Molecular enhancement of extracellular matrix and methods of use 2 2009
8,137,688 Hydroxyphenyl cross-linked macromolecular network and applications thereof 4 2009
* 2009/0252,700 Hydroxyphenyl cross-linked macromolecular network and applications thereof 2 2009
8,410,180 Methods to treat urinary incontinence 0 2009
* 2009/0274,678 Compositions and methods to treat urinary incontinence 0 2009
 
DEPUY SYNTHES PRODUCTS, LLC (23)
8,366,787 Hybrid biologic-synthetic bioabsorbable scaffolds 11 2002
8,337,537 Device from naturally occurring biologically derived materials 3 2002
8,092,529 Meniscus regeneration device 9 2002
8,025,896 Porous extracellular matrix scaffold and method 9 2002
8,012,205 Cartilage repair and regeneration device 8 2002
7,914,808 Hybrid biologic/synthetic porous extracellular matrix scaffolds 14 2002
7,361,195 Cartilage repair apparatus and method 100 2002
7,201,917 Porous delivery scaffold and method 42 2002
7,163,563 Unitary surgical device and method 94 2002
* 2003/0049,299 Porous delivery scaffold and method 12 2002
* 2003/0036,797 Meniscus regeneration device and method 126 2002
* 2003/0021,827 Hybrid biologic/synthetic porous extracellular matrix scaffolds 41 2002
7,160,333 Reinforced small intestinal submucosa 74 2003
7,819,918 Implantable tissue repair device 11 2003
7,513,866 Intestine processing device and associated method 0 2004
* 2006/0128,296 Intestine processing device and associated method 0 2004
7,569,233 Hybrid biologic-synthetic bioabsorbable scaffolds 4 2005
* 2005/0249,771 Hybrid biologic-synthetic bioabsorbable scaffolds 13 2005
7,595,062 Joint resurfacing orthopaedic implant and associated method 6 2005
* 2007/0100,460 Orthopaedic implant systems with anti-abrasion studs 5 2005
7,799,089 Reinforced small intestinal submucosa 7 2006
* 2007/0129,811 REINFORCED SMALL INTESTINAL SUBMUCOSA 6 2006
7,871,440 Unitary surgical device and method 6 2006
 
VELOCITY FINANCIAL GROUP INC., ITS SUCCESSORS AND ASSIGNS (3)
8,192,759 Matrix made of polyester polymers entangled with hyaluronic polymers useful for supporting tissue repair 1 2005
8,512,730 Methods of tissue repair and compositions therefor 0 2006
* 2006/0228,391 Methods of tissue repair and compositions therefor 68 2006
 
RTI SURGICAL, INC. (3)
* 6,893,462 Soft and calcified tissue implants 75 2001
* 2002/0072,806 Soft and calcified tissue implants 13 2001
7,513,910 Soft and calcified tissue implants 59 2004
 
BIOMET SPORTS MEDICINE, LLC (55)
7,608,092 Method and apparatus for performing meniscus repair 38 2004
7,608,098 Bone fixation device 79 2004
7,914,539 Tissue fixation device 34 2005
7,749,250 Soft tissue repair assembly and associated method 71 2006
* 8,034,090 Tissue fixation device 12 2006
8,998,949 Soft tissue conduit device 5 2006
7,658,751 Method for implanting soft tissue 103 2006
7,601,165 Method and apparatus for forming a self-locking adjustable suture loop 100 2006
9,017,381 Adjustable knotless loops 8 2007
7,857,830 Soft tissue repair and conduit device 48 2007
7,905,903 Method for tissue fixation 72 2007
7,909,851 Soft tissue repair device and associated methods 56 2008
7,905,904 Soft tissue repair device and associated methods 63 2008
8,251,998 Chondral defect repair 32 2008
8,137,382 Method and apparatus for coupling anatomical features 66 2008
8,128,658 Method and apparatus for coupling soft tissue to bone 52 2008
8,118,836 Method and apparatus for coupling soft tissue to a bone 70 2008
7,959,650 Adjustable knotless loops 66 2008
8,317,825 Soft tissue conduit device and method 36 2009
8,088,130 Method and apparatus for coupling soft tissue to a bone 45 2009
8,361,113 Method and apparatus for coupling soft tissue to a bone 37 2009
8,298,262 Method for tissue fixation 37 2009
8,303,604 Soft tissue repair device and method 34 2009
8,221,454 Apparatus for performing meniscus repair 36 2009
8,672,968 Method for implanting soft tissue 8 2010
9,078,644 Fracture fixation device 0 2010
8,801,783 Prosthetic ligament system for knee joint 7 2010
8,409,253 Soft tissue repair assembly and associated method 34 2010
8,562,647 Method and apparatus for securing soft tissue to bone 15 2010
8,597,327 Method and apparatus for sternal closure 14 2010
8,273,106 Soft tissue repair and conduit device 35 2010
8,337,525 Soft tissue repair device and associated methods 33 2011
8,292,921 Soft tissue repair device and associated methods 32 2011
8,652,171 Method and apparatus for soft tissue fixation 19 2011
8,562,645 Method and apparatus for forming a self-locking adjustable loop 15 2011
8,231,654 Adjustable knotless loops 62 2011
8,968,364 Method and apparatus for fixation of an ACL graft 6 2011
8,574,235 Method for trochanteric reattachment 1 2011
8,652,172 Flexible anchors for tissue fixation 15 2011
8,551,140 Method and apparatus for coupling soft tissue to bone 18 2011
8,672,969 Fracture fixation device 16 2011
8,506,597 Method and apparatus for interosseous membrane reconstruction 18 2011
8,936,621 Method and apparatus for forming a self-locking adjustable loop 6 2011
9,149,267 Method and apparatus for coupling soft tissue to a bone 0 2011
9,271,713 Method and apparatus for tensioning a suture 0 2011
8,840,645 Method and apparatus for coupling soft tissue to a bone 7 2012
8,932,331 Method and apparatus for coupling soft tissue to bone 6 2012
8,771,316 Method and apparatus for coupling anatomical features 13 2012
8,721,684 Method and apparatus for coupling anatomical features 12 2012
8,777,956 Chondral defect repair 12 2012
9,173,651 Soft tissue repair device and associated methods 0 2012
8,632,569 Soft tissue repair device and associated methods 14 2012
9,314,241 Apparatus for coupling soft tissue to a bone 0 2013
9,216,078 Method and apparatus for tibial fixation of an ACL graft 0 2013
9,005,287 Method for bone reattachment 5 2013
 
Ivoclar Vivadent, Inc. (1)
* 2007/0248,933 Methods for treating dental conditions using tissue scaffolds 6 2007
 
ISTO TECHNOLOGIES, INC. (1)
8,444,968 Cartilage repair methods 0 2006
 
REGENERATIVE SCIENCES, LLC (5)
* 2011/0200,642 Compositions and Methods to Promote Implantation and Engrafment of Stem Cells 5 2008
* 2010/0168,022 Use of In-Vitro Culture to Design or Test Personalized Treatment Regimens 6 2009
9,113,950 Therapeutic delivery device 0 2010
8,871,199 Compositions and methods to promote implantation and engrafment of stem cells 0 2012
9,168,261 Compositions and methods for cartilage repair 0 2013
 
REGENERATIVE SCIENCES, INC. (2)
9,095,562 Methods and compositions for optimized expansion and implantation of mesenchymal stem cells 0 2007
* 2009/0010,896 METHODS AND COMPOSITIONS FOR OPTIMIZED EXPANSION AND IMPLANTATION OF MESENCHYMAL STEM CELLS 6 2007
 
CELL SOLUTIONS COLORADO LLC (1)
* 2011/0054,929 Stem Cell Marketplace 5 2010
 
MICROPORT ORTHOPEDICS HOLDINGS INC. (5)
9,017,334 Patient specific surgical guide locator and mount 0 2010
* 2010/0217,338 Patient Specific Surgical Guide Locator and Mount 91 2010
9,113,914 Method for forming a patient specific surgical guide mount 0 2010
8,808,303 Orthopedic surgical guide 1 2011
9,089,342 Patient specific surgical guide locator and mount 0 2012
 
POREX SURGICAL (1)
8,142,886 Porous laser sintered articles 0 2008
 
ANIKA THERAPEUTICS S.R.L. (1)
* 7,722,616 Use of a biological material containing three-dimensional scaffolds of hyaluronic acid derivatives for the preparation of implants in arthroscopy and kit for instruments for implanting said biological material by arthroscopy 0 2001
 
BIOMETRIX CORPORATION (1)
* 2010/0256,777 At least partially resorbable reticulated elastomeric matrix elements and methods of making same 4 2010
 
IMDS CORPORATION (2)
8,636,780 Line lock graft retention system and method 0 2009
8,388,655 Compact line locks and methods 5 2010
 
ABS CORPORATION (3)
* 6,632,246 Cartilage repair plug 83 2000
6,626,945 Cartilage repair plug 171 2001
6,852,125 Cartilage repair plug 45 2003
 
Zimmer Orthobiologics, Inc. (2)
RE43714 Preparation for repairing cartilage defects or cartilage/bone defects in human or animal joints 6 2000
8,497,121 Method of obtaining viable small tissue particles and use for tissue repair 8 2012
 
Musculoskeletal Transplant Foundation (10)
7,901,457 Cartilage allograft plug 30 2003
7,488,348 Cartilage allograft plug 28 2005
7,815,926 Implant for articular cartilage repair 7 2006
7,837,740 Two piece cancellous construct for cartilage repair 20 2007
RE42208 Glue for cartilage repair 19 2008
8,221,500 Cartilage allograft plug 7 2008
8,435,551 Cancellous construct with support ring for repair of osteochondral defects 3 2009
8,906,110 Two piece cancellous construct for cartilage repair 0 2010
RE43258 Glue for cartilage repair 5 2010
8,292,968 Cancellous constructs, cartilage particles and combinations of cancellous constructs and cartilage particles 4 2011
 
IMDS LLC (1)
9,265,498 Compact line locks and methods 0 2013
 
MEDTRONIC PS MEDICAL, INC. (1)
6,572,623 Method and apparatus for attaching a cranial flap 8 2000
 
BIOMERIX CORPORATION (5)
7,763,077 Repair of spinal annular defects and annulo-nucleoplasty regeneration 24 2003
7,803,395 Reticulated elastomeric matrices, their manufacture and use in implantable devices 12 2004
* 2005/0043,816 Reticulated elastomeric matrices, their manufacture and use in implantable devices 41 2004
8,801,801 At least partially resorbable reticulated elastomeric matrix elements and methods of making same 0 2010
9,050,176 At least partially resorbable reticulated elastomeric matrix elements and methods of making same 0 2012
 
The University of Liverpool (6)
8,268,100 Laser-produced porous surface 18 2010
* 2010/0291,286 LASER-PRODUCED POROUS SURFACE 2 2010
* 2011/0014,081 LASER-PRODUCED POROUS STRUCTURE 18 2010
9,135,374 Surface modified unit cell lattice structures for optimized secure freeform fabrication 0 2012
8,992,703 Laser-produced porous surface 0 2012
9,180,010 Surface modified unit cell lattice structures for optimized secure freeform fabrication 0 2012
 
Orthogene LLC (3)
6,630,457 Functionalized derivatives of hyaluronic acid, formation of hydrogels in situ using same, and methods for making and using same 39 1998
7,196,180 Functionalized derivatives of hyaluronic acid, formation of hydrogels in situ using same, and methods for making and using same 44 2003
* 2004/0072,793 Functionalized derivatives of hyaluronic acid, formation of hydrogels in situ using same, and methods for making and using same 2 2003
 
COVIDIEN LP (3)
6,712,822 Apparatus and method for the repair of articular cartilage defects 35 2002
8,157,805 Apparatus and method for the repair of articular cartilage defects 1 2004
* 2004/0181,232 Apparatus and method for the repair of articular cartilage defects 7 2004
 
MASSACHUSETTS INSTITUTE OF TECHNOLOGY (1)
7,815,826 Manufacturing process, such as three-dimensional printing, including solvent vapor filming and the like 14 2005
 
ChondoSite, LLC (1)
* 2004/0162,622 Cartilage repair plug 23 2003
 
ALLOSOURCE (1)
9,289,452 Consistent calcium content bone allograft systems and methods 0 2014
 
ULTRA TEC MANUFACTURING, INC. (1)
* 2004/0039,447 Cartilage repair plug 58 2003
 
LAWLER, JOHN (1)
6,849,594 Purification and use of human recombinant cartilage oligomeric matrix protein 3 2000
 
MedIdea, LLC (1)
* 2001/0043,918 In vitro mechanical loading of musculoskeletal tissues 25 2001
 
MEDICINE LODGE (DBA IMDS CO-INNOVATION) (1)
8,771,352 Method and apparatus for tibial fixation of an ACL graft 14 2011
 
BONUTTI SKELETAL INNOVATIONS LLC (28)
6,702,821 Instrumentation for minimally invasive joint replacement and methods for using same 291 2001
* 2002/0029,045 Method of performing surgery 60 2001
6,770,078 Movable knee implant and methods therefor 204 2001
7,104,996 Method of performing surgery 156 2002
7,635,390 Joint replacement component having a modular articulating surface 62 2003
8,133,229 Knee arthroplasty method 18 2003
7,806,896 Knee arthroplasty method 191 2003
7,959,635 Limited incision total joint replacement methods 15 2004
7,892,236 System and method for total joint replacement 22 2005
7,510,557 Cutting guide 49 2005
7,806,897 Knee arthroplasty and preservation of the quadriceps mechanism 36 2005
7,749,229 Total knee arthroplasty through shortened incision 40 2005
7,708,740 Method for total knee arthroplasty and resecting bone in situ 34 2005
7,708,741 Method of preparing bones for knee replacement surgery 53 2005
7,931,690 Method of resurfacing an articular surface of a bone 22 2007
7,828,852 Inlaid articular implant 26 2007
7,837,736 Minimally invasive surgical systems and methods 33 2007
8,425,522 Joint replacement method 31 2010
8,784,495 Segmental knee arthroplasty 1 2010
9,101,443 Methods for robotic arthroplasty 1 2012
8,641,726 Method for robotic arthroplasty using navigation 13 2013
8,632,552 Method of preparing a femur and tibia in knee arthroplasty 12 2013
8,623,030 Robotic arthroplasty system including navigation 12 2013
8,858,557 Method of preparing a femur and tibia in knee arthroplasty 3 2013
8,840,629 Robotic arthroplasty system including navigation 3 2013
8,834,490 Method for robotic arthroplasty using navigation 4 2013
9,192,459 Method of performing total knee arthroplasty 0 2014
9,060,797 Method of preparing a femur and tibia in knee arthroplasty 0 2014
 
DEPUY PRODUCTS, INC. (8)
* 7,666,230 Implant device for cartilage regeneration in load bearing articulation regions 15 2003
* 2005/0125,073 Implant device for cartilage regeneration in load bearing articulation regions 64 2003
* 2005/0137,600 Articular cartilage repair implant delivery device and method of use 102 2003
* 2004/0166,169 Porous extracellular matrix scaffold and method 95 2004
7,354,627 Method for organizing the assembly of collagen fibers and compositions formed therefrom 15 2004
8,216,319 Method of repairing a knee joint 0 2005
* 2007/0100,459 Method of repairing a knee joint 10 2005
8,128,703 Fixed-bearing knee prosthesis having interchangeable components 11 2009
 
DEPUY SPINE, INC. (2)
6,645,945 Method of treating diseased, injured or abnormal cartilage with hyaluronic acid and growth factors 8 1999
7,902,172 Method of promoting bone growth with hyaluronic acid and growth factors 0 2004
 
DEPUY ORTHOPAEDICS, INC. (4)
6,251,143 Cartilage repair unit 279 1999
6,468,314 Cartilage repair unit 135 2001
* 7,172,606 Soft tissue repair material fixation apparatus and method 2 2003
* 2003/0105,477 Soft tissue repair material fixation apparatus and method 34 2003
 
MEDICINELODGE, INC. DBA IMDS CO-INNOVATION (7)
7,488,347 Transosseous graft retention system and method 3 2005
7,641,694 Line lock graft retention system and method 3 2005
7,722,644 Compact line locks and methods 8 2005
* 2006/0190,041 Compact line locks and methods 7 2005
* 2006/0276,896 Bone implants with integrated line locks 29 2005
* 2010/0191,285 Compact Line Locks and Methods 0 2010
* 2010/0305,585 LINE LOCK THREADING SYSTEMS AND METHODS 2 2010
 
VERIGEN AG (7)
6,866,668 Methods, instruments and materials for chondrocyte cell transplantation 21 2001
* 2002/0045,940 Methods, instruments and materials for chondrocyte cell transplantation 85 2001
* 2004/0136,968 Autologous cells on a support matrix for tissue repair 13 2003
* 2006/0025,786 Method for autologous transplantation 1 2004
* 2005/0129,668 Methods, instruments and materials for chondrocyte cell transplantation 11 2005
* 2006/0167,483 Method, instruments, and kit for autologous transplantation 14 2006
* 2007/0212,396 Autologous cells on a support matrix for tissue repair 2 2007
 
BIORESTORATIVE THERAPIES, INC. (1)
9,133,438 Brown fat cell compositions and methods 0 2012
 
THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (9)
8,265,730 Assessing the condition of a joint and preventing damage 68 2001
8,036,729 Assessing the condition of a joint and devising treatment 110 2004
9,286,686 Assessing the condition of a joint and assessing cartilage loss 0 2007
7,881,768 Assessing the condition of a joint and devising treatment 130 2007
8,112,142 Assessing the condition of a joint and devising treatment 96 2007
RE43282 Assessing the condition of a joint and devising treatment 106 2008
8,369,926 Assessing the condition of a joint and devising treatment 67 2011
8,306,601 Assessing the condition of a joint and devising treatment 85 2011
8,862,202 Assessing the condition of a joint and preventing damage 2 2012
 
TRUSTEES OF TUFTS COLLEGE (1)
6,287,340 Bioengineered anterior cruciate ligament 53 1999
 
THE RESEARCH FOUNDATION OF STATE UNIVERSITY OF NEW YORK (2)
* 6,312,952 In vitro cell culture device including cartilage and methods of using the same 6 2000
6,465,205 In vitro cell culture device including cartilage and methods of using the same 24 2001
 
University of Massachusetts (1)
* 2004/0034,357 Controlled release implantable devices 225 2003
 
ARTHROSURFACE, INC. (35)
* 7,678,151 System and method for joint resurface repair 46 2003
* 2003/0225,456 System and method for joint resurface repair 79 2003
7,510,558 System and method for joint resurface repair 40 2003
* 2004/0015,170 System and method for joint resurface repair 67 2003
7,618,462 System and method for joint resurface repair 46 2004
* 2004/0230,315 Articular surface implant 54 2004
7,896,885 Retrograde delivery of resurfacing devices 29 2004
8,361,159 System for articular surface replacement 12 2005
* 2006/0085,006 System and method for retrograde procedure 38 2005
7,914,545 System and method for retrograde procedure 30 2006
7,828,853 Articular surface implant and delivery system 25 2006
7,713,305 Articular surface implant 32 2006
* 2007/0005,143 Articular surface implant and delivery system 40 2006
* 2007/0179,608 SYSTEM AND METHOD FOR ARTICULAR SURFACE REPAIR 41 2006
7,951,163 Retrograde excision system and apparatus 20 2006
8,523,872 Tibial resurfacing system 10 2007
8,177,841 System and method for joint resurface repair 19 2008
* 2008/0195,113 Bone Cement Delivery Device 19 2008
7,896,883 Bone resurfacing system and method 22 2009
7,857,817 System and method for joint resurface repair 23 2009
8,147,559 System and method for joint resurface repair 18 2009
* 2010/0070,048 System and Method for Joint Resurface Repair 3 2009
8,388,624 Trochlear resurfacing system and method 13 2010
8,540,717 System and method for joint resurface repair 9 2010
9,283,076 Glenoid resurfacing system and method 0 2010
8,961,614 Articular surface implant and delivery system 5 2010
9,055,955 Bone resurfacing system and method 2 2011
8,663,230 Retrograde delivery of resurfacing devices 8 2011
8,556,902 System and method for retrograde procedure 0 2011
8,926,615 System and method for retrograde procedure 7 2011
9,066,716 Suture coil and suture sheath for tissue repair 2 2012
* 9,204,873 System and method for joint resurface repair 1 2012
* 2012/0191,187 System and Method for Joint Resurface Repair 3 2012
8,864,827 System and method for joint resurface repair 7 2012
9,044,343 System for articular surface replacement 2 2013
 
Active Implants Corporation (9)
* 2008/0255,665 ANCHORED PROSTHETIC MENISCUS DEVICE 4 2007
8,192,491 Meniscus prosthetic device 1 2007
* 2008/0086,210 Meniscus Prosthetic Device 26 2007
8,361,147 Meniscus prosthetic devices with anti-migration features 3 2008
8,016,884 Tensioned meniscus prosthetic devices and associated methods 8 2008
7,991,599 Meniscus prosthetic device selection and implantation methods 4 2008
7,611,653 Manufacturing and material processing for prosthetic devices 57 2008
* 2009/0259,311 Tensioned Meniscus Prosthetic Devices and Associated Methods 12 2008
* 2009/0259,313 MANUFACTURING AND MATERIAL PROCESSING FOR PROSTHETIC DEVICES 5 2008
 
Biomet Sports Medicine (1)
8,608,777 Method and apparatus for coupling soft tissue to a bone 15 2011
 
BIOMET MANUFACTURING, LLC (18)
7,837,690 Method and apparatus for less invasive knee resection 28 2003
7,488,324 Femoral guide for implanting a femoral knee prosthesis 45 2003
7,887,542 Method and apparatus for less invasive knee resection 13 2004
7,789,885 Instrumentation for knee resection 31 2005
7,695,479 Femoral sizer 5 2005
8,551,100 Instrumentation for knee resection 3 2006
7,780,672 Femoral adjustment device and associated method 54 2006
7,695,520 Prosthesis and implementation system 16 2006
8,070,752 Patient specific alignment guide and inter-operative adjustment 73 2008
8,123,758 Femoral guide for implanting a femoral knee prosthesis 6 2009
8,500,818 Knee prosthesis assembly with ligament link 26 2010
8,343,227 Knee prosthesis assembly with ligament link 23 2010
8,518,047 Method and apparatus for less invasive knee resection 3 2010
8,870,883 Method for less invasive knee resection 0 2011
9,259,217 Suture Button 0 2012
8,834,486 Femoral guide for implanting a femoral knee prosthesis 0 2012
8,900,314 Method of implanting a prosthetic knee joint assembly 4 2012
9,023,053 Instrumentation for knee resection 0 2013
 
DEPUY (IRELAND) (2)
9,011,547 Knee prosthesis system 0 2010
9,204,967 Fixed-bearing knee prosthesis having interchangeable components 0 2013
 
VERICEL CORPORATION (8)
6,569,172 Method, instruments, and kit for autologous transplantation 44 2001
6,592,598 Method, instruments, and kit for autologous transplantation 19 2002
6,599,300 Method, instruments, and kit for autologous transplantation 13 2002
6,592,599 Method, instruments, and kit for autologous transplantation 15 2002
6,599,301 Method, instruments, and kit for autologous transplantation 24 2002
7,137,989 Method, instruments, and kit for autologous transplantation 12 2003
7,048,750 Method, instruments, and kits for autologous transplantation 11 2003
* 2003/0195,532 Method, instruments, and kit for autologous transplantation 0 2003
 
DEPUY ACROMED, INC. (1)
* 2004/0176,295 Method of promoting bone growth with hyaluronic acid and growth factors 0 2004
 
DEPUY MITEK, INC. (6)
8,110,210 Nonwoven tissue scaffold 0 2004
8,016,867 Graft fixation device and method 2 2004
* 2006/0067,967 Reinforced foam implants with enhanced integrity for soft tissue repair and regeneration 26 2005
8,105,621 Nonwoven tissue scaffold 0 2006
7,875,296 Conformable tissue repair implant capable of injection delivery 63 2007
8,137,702 Conformable tissue repair implant capable of injection delivery 29 2010
 
Martec, LLC (1)
7,615,054 Bicompartmental knee implant and method 111 2003
* Cited By Examiner