Detection of mutations in the human ATM gene
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United States of America Patent
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Jun 23, 1998
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app pub date -
Nov 20, 1996
filing date -
Nov 20, 1996
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Abstract
This invention pertains to methods for detecting mutations in the human ataxia telangiectasia (ATM) gene. The invention provides DNA sequences immediately flanking the exons in the 3' half of the gene. Also provided are primers that can be used in the polymerase chain reaction to amplify segments of the ATM gene corresponding to each of the 65 coding exons including its immediately flanking sequences. A number of mutations found in the human ATM gene are described also.
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