Cloning and exprssion of humanized monoclonal antibodies against human interluekin-4
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United States of America Patent
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Jun 23, 1998
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app pub date -
Jun 6, 1995
filing date -
Feb 19, 1992
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Abstract
Monoclonal antibodies are provided which are specific for human interleukin-4. Also provided are complementary DNAs which encode the heavy and light chain variable regions of such monoclonal antibodies and complementarity determining regions from such DNAs; and kits and methods for detecting, measuring and immunopurifying human interleukin-4, and for blocking the biological activity of human interleukin-4.
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