Ophthalmic preparation for use as artificial tear

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United States of America Patent

PATENT NO 5770628
SERIAL NO

08505095

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ATTORNEY / AGENT: (SPONSORED)

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Abstract

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Ophthalmic preparation for use as artificial tear containing hyaluronate as a viscosity thickener, preferably in the form of sodic salt and having a molecular weight of 500,000 to 4,000,000 daltons, at a concentration of 0.05 to 2% by weight, as well as the following minimum quantities of ionic species: 40 mmol/l sodium ion, 12 mmol/l potassium ion, 0.4 mmol/l calcium ion, 0.4 mmol/l magnesium ion, 50 mmol/l chloride ion, 7 mmol/l phosphate ion and, preferably, 0.7 mmol/l citrate ion. The formulation, which as an osmolarity of 140 to 280 mOsm/l, is useful for the treatment of keratoconjunctivitis sicca and may be administered whenever the use of artifical tears is advisable, e.g. for the treatment of eye irritations caused by environmental conditions or contact lenses.

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Patent Owner(s)

Patent OwnerAddress
LABORATOIRE MEDIDOM S AGENEVA SWITZERLAND GENEVE GENEVA

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Cantoro, Amalio Bologna, IT 3 58

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