Methods and apparatus for making liposomes containing hydrophobic drugs
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United States of America Patent
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Jul 7, 1998
Issued Date -
N/A
app pub date -
Apr 12, 1996
filing date -
May 28, 1993
priority date (Note) -
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Abstract
The present application features methods and apparatus for making liposomes containing hydrophobic drugs, with critical, supercritical or near critical fluids. The methods and apparatus combine a phospholipid, a drug, and an aqueous phase, or multilamellar vesicles, with a critical, supercritical or near critical fluid. Upon a reduction in pressure, liposomes are formed.
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