Phosphocholines of retinoids
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United States of America Patent
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Jul 7, 1998
Grant Date -
N/A
app pub date -
Aug 12, 1997
filing date -
Aug 12, 1997
priority date (Note) -
Expired
status (Latency Note)
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Abstract
Novel retinoid phosphocholines are disclosed having the general Formula (I): ##STR1## wherein R represents a retinyl or retinoyl moiety. The optical and geometric isomers of compounds of Formula (I) and the pharmaceutically-acceptable salts thereof, are also disclosed. The subject compounds exhibit anti-tumor, anti-psoriatic and anti-inflammatory activities in addition to their inherent Vitamin A-like activities. The invention embraces the novel compounds, pharmaceutical compositions thereof, and methods of using the same.
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