Peripheral benzodiazepine receptor ligands as antiinflammatory agents

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United States of America Patent

PATENT NO 5776946
SERIAL NO

08520211

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Abstract

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Compounds which bind with high affinity to peripheral benzodiazepine receptors are useful as antiinflammatory agents. Such compounds include isoquinoline and benzodiazepine derivatives, such as PK 11195. A method of treating an inflammatory condition in a mammal with such compounds is provided. Pharmaceutical compositions comprising such compounds are provided. A method is provided for identifying compounds that are therapeutically effective for treating inflammatory conditions.

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Patent Owner(s)

Patent OwnerAddress
MCGEER PATRICK LUBC HOSPITAL DETWILLER PAVILLION 1 2255 WESBROOK MALL VANCOUVER V6T 2A1
MCGEER EDITH GUBC HOSPITAL DETWILLER PAVILLION 1 2255 WESBROOK MALL VANCOUVER V6T 2A1
WATERFIELD DOUGLAS JUBC HOSPITAL DETWILLER PAVILLION 1 2255 WESBROOK MALL VANCOUVER V6T 2A1

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
McGeer, Edith G Kinsmen Laboratory of Neurological Research, The University of British, Vancouver, British Columbia, CA 7 47
McGeer, Patrick L Kinsmen Laboratory of Neurological Research, The University of British, Vancouver, British Columbia, CA 18 304
Waterfield, J Douglas Kinsmen Laboratory of Neurological Research, The University of British, Vancouver, British Columbia, CA 1 36

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